نتایج جستجو برای: pldh

تعداد نتایج: 124  

2017
Nguyen Thi Phuong Linh Hyun Park Jinyoung Lee Dong-Xu Liu Ga-Eun Seo Hae-Jin Sohn Jin-Hee Han Eun-Taek Han Ho-Joon Shin Seon-Ju Yeo

Plasmodium lactate dehydrogenase (pLDH) is a strong target antigen for the determination of infection with Plasmodium species specifically. However, a more effective antibody is needed because of the low sensitivity of the current antibody in many immunological diagnostic assays. In this study, recombinant Plasmodium vivax LDH (PvLDH) was experimentally constructed and expressed as a native ant...

2014
Dandan Niu Kangming Tian Bernard A Prior Min Wang Zhengxiang Wang Fuping Lu Suren Singh

UNLABELLED L-Lactic acid, one of the most important chiral molecules and organic acids, is produced via pyruvate from carbohydrates in diverse microorganisms catalyzed by an NAD+-dependent L-lactate dehydrogenase. Naturally, Escherichia coli does not produce L-lactate in noticeable amounts, but can catabolize it via a dehydrogenation reaction mediated by an FMN-dependent L-lactate dehydrogenase...

Journal: :Journal of clinical microbiology 1998
C J Palmer J F Lindo W I Klaskala J A Quesada R Kaminsky M K Baum A L Ager

The development of rapid and specific diagnostic tests to identify individuals infected with malaria is of paramount importance in efforts to control the severe public health impact of this disease. This study evaluated the ability of a newly developed rapid malaria diagnostic test, OptiMAL (Flow Inc., Portland, Oreg.), to detect Plasmodium vivax and Plasmodium falciparum malaria during an outb...

Journal: :Acta tropica 2013
Rachida Tahar Collins Sayang Vincent Ngane Foumane Georges Soula Roger Moyou-Somo Jean Delmont Leonardo K Basco

Rapid diagnostic tests (RDTs) are affordable, alternative diagnostic tools. The present study aimed to evaluate RDTs available in Cameroon and compare their characteristics to follow the parasitological response of patients for 28 days. Malaria diagnosis was assessed in 179 febrile patients using conventional microscopy as the reference method. Parascreen detects both Plasmodium falciparum-spec...

2013
Bethel Kwansa-Bentum Shinji Izumiyama Kei Kitamura Kazushige Obata-Ninomiya Nobuo Ohta Hiroko Asahi

Malaria continues to be a devastating disease. In a previous study, we formulated a chemically defined culture medium that is able to sustain the complete intraerythrocytic growth of Plasmodium falciparum. We tested the feasibility of using the medium (CDRPMI) as well as human serum-free media enriched with commercially available human-serum substitutes (GFSRPMI and ALBRPMI) to assess the drug ...

2017
Yongping Xin Tingting Guo Yingli Mu Jian Kong

BACKGROUND Lactic acid bacteria (LAB) are receiving more attention to act as cell factories for the production of high-value metabolites. However, the molecular tools for genetic modifying these strains are mainly vector-based double-crossover strategies, which are laborious and inefficient. To address this problem, several counterselectable markers have been developed, while few of them could ...

2015
Bridget E. Barber Timothy William Matthew J. Grigg Uma Parameswaran Kim A. Piera Ric N. Price Tsin W. Yeo Nicholas M. Anstey

Plasmodium vivax can cause severe malaria, however its pathogenesis is poorly understood. In contrast to P. falciparum, circulating vivax parasitemia is low, with minimal apparent sequestration in endothelium-lined microvasculature, and pathogenesis thought unrelated to parasite biomass. However, the relationships between vivax disease-severity and total parasite biomass, endothelial autocrine ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید