In the early phase of their disease process, patients with acute lung injury are often ventilated with strategies that control the tidal volume or airway pressure, while modes employing spontaneous breathing are applied later to wean the patient from the ventilator. Spontaneous breathing modes may integrate intrinsic feedback mechanisms that should help prevent ventilator-induced lung injury, a...

The wet air oxidation (WAO) of municipal landfill leachate catalyzed by cupric ions and promoted by hydrogen peroxide was investigated. The effect of operating conditions such as WAO treatment time (15-30min), temperature (160-200°C), Cu(2+) concentration (250-750mgL(-1)) and H(2)O(2) concentration (0-1500mgL(-1)) on chemical oxygen demand (COD) removal was investigated by factorial design cons...

I show that US prescription drug prices can be better understood by accounting for history-dependent demand and industry pricing structure, which has important implications for potential government negotiation. First, I confirm the presence of inertia and history-dependent demand for generic drugs through a novel quasiexperiment. Next, I capture pricing structure in a dynamic pricing game invol...

This study proposes a new multi-item inventory model with hybrid cost parameters under a fuzzy-stochastic constraint and permissible delay in payment. The price and marketing expenditure dependent stochastic demand and the demand dependent the unit production cost are considered. Shortages are allowed and partially backordered. The main objective of this paper is to determine selling price, mar...

Bark leachate is generated from sawmill operations such as log storage sites and contains polymeric tannins, carbohydrates, organic acids, phenolic and resin compounds. The present study was aimed at assessing the performance of a sequential anaerobic and aerobic treatment, for both chemical oxygen demand (COD) and phenol removal, under various combinations of operational conditions, in the con...

Money demand determinants vary in every economy. There are many studies about Iran money demand function, which employed different variables and estimation methods. In this study, broad money (M2) is dependent variable and GDP, interest rate, exchange rate and household religious costs are descriptive variables. Household religious costs (urban and rural) are included in Iran money demand funct...

The diastolic pressure-volume curve shifts upward during demand ischemia, most likely because of changes in Ca2+ dynamics within the sarcomere. It is possible that agents that affect Na+/Ca2+exchange, such as lidocaine, a class 1b-type Na+-channel blocker that decreases intracellular Na+, could affect the diastolic pressure-volume relationship because of indirect effects on intracellular Ca2+. ...

This paper investigates the implications of an intertemporally dependent demand structure in the market for an exhaustible resource. The demand structure is derived endogenously in a partial equilibrium model where price-taking users combine the resource with capital to produce final output. It is shown that, when demand for the resource is modelled explicitly as a derived demand, the common as...

We study a manufacturing firm that builds a product to stock to meet a random demand. Production time is deterministic, so that if there is a backlog, customers are quoted a firm lead time that is proportional to the backlog. In order to represent the customers’ response to waiting, we introduce a new defection function — the probability that a customer chooses not to order as a function of the...