Background: Helicobacter pylori (H.pylori) is a common bacterial infection, with considerably high morbidity and mortality worldwide. This bacterium represents a key factor in the etiology of various chronic infections ranging from gastritis, peptic ulcer disease to gastric cancer; but the prevalence has large variations in different communities. The aim of this study was to estimate the preval...

Background: It is not yet known which types of Toll-like receptors (TLRs) are most effective in Helicobacter pylori (H. pylori) recognition. It is also not known which gastric zones have the most prominent roles in TLR-mediated bacterial recognition. The aim of this work was to analyze the expression of TLR2 and TLR4 in biopsy specimens from H. pylori-infected patients. Methods: Thirty-eight...

Helicobacter pylori is the causative agent of gastritis and peptic ulcer disease. Eradication of H. pylori is hard to achieve and often require multiple antibiotics regimens. These regimens are quite expensive and have substantial side effects. Licorice is a traditional drug which is frequently used for gastric discomforts in Iran. The susceptibility of H. pylori to the extract of licorice has ...

BACKGROUND Gastric mucosa associated lymphoid tissue (MALT) lymphomas are clinically subdivided into Helicobacter pylori dependent and independent, according to H. pylori infection and the therapeutic course. In previous reports it has been suggested that H. pylori independent cases develop from H. pylori dependent cases, and sometimes transform into high grade diffuse large B cell lymphomas (D...

Background: Risk of recurrent bleeding from Helicobacter pylori-negative ulcers is greater than for H pylori ulcers, but to what degree is unknown. Objective: To determine the risk of rebleeding for peptic ulcers with and without associated H pylori infection. Design: Prospective cohort study in 1 institution over 7 years. Participants: 120 patients had H pylori-negative peptic ulcer bleeding a...

Aims: The objective of this retrospective study was to evaluate the prevalence Helicobacter pylori (H. pylori) positivity, gastric atrophy, and intestinal metaplasia in patients with dyspeptic complaints who had undergone total hip knee replacement surgeries, compared a control group without prosthesis.
 Methods: consisted 51 prosthesis, while comprised 75 similar but prosthesis. Endoscopi...

Previous studies suggested that polymorphisms of proinflammatory cytokine genes are important host genetic factors in Helicobacter pylori infection. The present study evaluated whether IL-8-251 polymorphism affected H. pylori eradication rate and to investigate the effect of H. pylori eradication on angiogenesis and the inflammatory process according to the IL-8-251 polymorphism. A total of 250...

Humans always mount a robust immune response to the bacterial infection caused by Helicobacter pylori, which causes various gastrointestinal tract infections. Calprotectin (CALP) and B-Cell Activating Factor (BAFF) are inflammatory biomarkers having role in neutrophilic infection. The study was designed assess serum CALP BAFF as H. pylori peptic ulcer patients. current comprised 112 people, inc...

Background: Globally obesity is a commonly health condition. A great number of investigators have been studying the association between Helicobacter pylori (H. pylori) infection and obesity. It’s also known that H. causes inflammation within mucosa stomach which as gastritis. However, due to arguable data in literature, relationship Pylori remains debatable there no comprehensive proof for asso...

INTRODUCTION Although it is incontrovertible that Helicobacter pylori causes peptic ulcer disease, controversy persists regarding the impact of H. pylori infection on the incidence of NSAID-related complications and whether H. pylori eradication reduces the rate of adverse events. METHODS A symptom-driven decision analytic model was developed to compare the clinical and economic impact of H. ...