نتایج جستجو برای: radioprotective agents
تعداد نتایج: 361447 فیلتر نتایج به سال:
Benzimidazole and its derivatives are used in organic synthesis and they are used in evaluating new product that possesses different biological activities. This review article covers the most active benzimidazole derivatives that have shown considerable biological actions such as antimicrobial, anti-inflammatory, anticancer, anticonvulsant, antidepressant, antioxidant, radioprotective and anti-...
A majority of potential radioprotective synthetic compounds have demonstrated limited clinical application owing to their inherent toxicity, and thus, the seeking of naturally occurring herbal products, such as ginseng, for their radioprotective capability has become an attractive alternative. In general, ginseng refers to the roots of the species of the genus Panax. As a medicinal herb, ginsen...
Superoxide dismutase (SOD) fusion of TAT was proved to be radioprotective in our previous work. On that basis, a bifunctional recombinant protein which was the fusion of glutathione S-transferase (GST), SOD, and TAT was constructed and named GST-TAT-SOD. Herein we report the investigation of the cytotoxicity, cell-penetrating activity, and in vitro radioprotective effect of GST-TAT-SOD compared...
Radioprotective effects of ethanolic extracts Gongronema latifolium leaf against radiation induced oxidative stress in Wistar albino Rats
The radioprotective effects of dimethyl sulfoxide (DMSO) have been known for many years, and the suppression of hydroxyl (OH) radicals induced by ionizing radiation has been thought to be the main cause of this effect. However, the DMSO concentration used was very high, and might be toxic, in earlier studies. In the present study, we administered a lower, non-toxic concentration (0.5%, i.e., 64...
BACKGROUND/OBJECTIVES Exposure of the normal lung tissue around the cancerous tumor during radiotherapy causes serious side effects such as pneumonitis and pulmonary fibrosis. Radioprotectors used during cancer radiotherapy could protect the patient from side effects induced by radiation injury of the normal tissue. Delphinidin has strong antioxidant properties, and it works as the driving forc...
Aims: More people, for occupational and therapeutic purposes, is exposed to its harmful effects including chromosomal abnormalities every day. Radioprotective agents are able to reduce these kinds of damages through mechanisms such as free radical scavenging, donating hydrogen to damaged molecules and increasing activity of antioxidant enzymes. Medicinal plants which have been traditionally use...
This is the second article published in the Trees for Life Journal which deals with radioprotection (see http://www. tfljournal.org/article.php/2007042416194363 by Sancheti and Goyal). While it is not a major focus of this journal, radioprotection has interest for our readership and is attracting ever more attention within the scientific community. No synthetic radioprotective chemicals are ava...
RLIP76 (RALBP1) is a glutathione-conjugate transporter that is a critical component of clathrin-coated pit-mediated endocytosis, as well as in stress responses. In cultured cells, it provides protection from stressors including heat, oxidant chemicals, chemotherapeutic agents, UV irradiation, and X-irradiation. Here, we show marked reduction in glutathione conjugate transport capacity and stepw...
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