Shokohozaman Soleymanifard

Department of Medical Physic, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

[ 1 ] - Origanum vulgare leaf extract protects mice bone marrow cells against ionizing radiation

Objective: Ionizing radiation produces free radicals which induce DNA damage and cell death. Origanum vulgare leaf extract (OVLE) is a natural compound and its capability of scavenging free radicals and its antioxidant activity have been demonstrated by many researchers. In this study, using micronucleus assay, radioprotective effect of OVLE against clastogenic and cytotoxic effect of gamma irr...

[ 2 ] - Assessment of Dose Calculation Accuracy of TiGRT Treatment Planning System for Physical Wedged fields in Radiotherapy

Introduction Wedge modifiers are commonly applied in external beam radiotherapy to change the dose distribution corresponding to the body contour and to obtain a uniform dose distribution within the target volume. Since the radiation dose delivered to the target must be within ±5% of the prescribed dose, accurate dose calculation by a treatment planning system (TPS) is important. The objective ...

[ 3 ] - An Investigation of the Effects of Raw Garlic on Radiation-induced Bystander Effects in MCF7 Cells

Introduction Radiation-induced bystander effect (RIBE) is a phenomenon in which radiation signals are transmitted from irradiated cells to non-irradiated ones, inducing radiation effects in these cells. RIBE plays an effective role in radiation response at environmentally relevant low doses and in radiotherapy, given its impact on adjacent normal tissues or those far from the irradiated tumor. ...

[ 4 ] - Evaluation of Dose Calculation Accuracy of Isogray Treatment Planning System in Craniospinal Radiotherapy

Introduction: Craniospinal radiotherapy is a therapeutic technique for central nervous system (CNS) tumors, which requires meticulous attention to technique and dosimetry.Treatment planning system (TPS) is one of the main equipment in radiotherapy; therefore, the evaluation of its accuracy is essential for dose calculation. The present study evaluates the validity of Isogray TPS in craniospinal...

[ 5 ] - The role of dose fractionation in the level of Radiation- Induced Bystander Effect in QU-DB Cells

Introduction: Radiation effects induced in non-irradiated cells are termed radiation- induced bystander effects (RIBE). The present study intends to examine the RIBE response of QU-DB bystander cells to first, second and third radiation fractions and compare their cumulative outcome with an equal, single acute dose.   Materials and Methods: This experimental ...

[ 6 ] - Invesitgating the Radioprotective Effect of Brewed Rosa damascene in Comparison with Vitamin E on X-ray Induced Chromosomal Aberrations in Human Peripheral Blood Lymphocytes Using Micronucleus Assay in Binucleated Cells

Aims: More people, for occupational and therapeutic purposes, is exposed to its harmful effects including chromosomal abnormalities every day. Radioprotective agents are able to reduce these kinds of damages through mechanisms such as free radical scavenging, donating hydrogen to damaged molecules and increasing activity of antioxidant enzymes. Medicinal plants which have been traditionally use...