BACKGROUND β-Mannanase randomly cleaves the β-1,4-linked mannan backbone of hemicellulose, which plays the most important role in the enzymatic degradation of mannan. Although the industrial applications of β-mannanase have tremendously expanded in recent years, the wild-type β-mannanases are still defective for some industries. The glycoside hydrolase (GH) family 5 β-mannanase (RmMan5A) from R...

Y75N mutant Mucor pusillus pepsin has been overexpressed in yeast, purified and cocrystallized with the iodine-containing human renin inhibitor CP-113972 [(2R,3S]-isopropyl 3-[(L-prolyl-p-iodo-L-phenylalanyl-S-methyl-cysteinyl)amino-4]-cyclohexyl-2-hydroxybutanoate] for X-ray crystallography. Tetragonal complex crystals with space group P4(3)2(1)2 were produced by the hanging-drop vapour-diffus...

Most isolates belonging to the Bacillus amyloliquefaciens subsp. plantarum clade retain the potential to produce a vast array of structurally diverse antimicrobial compounds that largely contribute to their efficacy as biocontrol agents against numerous plant fungal pathogens. In that context, the role of cyclic lipopeptides (CLPs) has been well-documented but still little is known about the im...

We present a case of 63-year-old hematologic patient with pulmonary vaso-invasive zygomycosis Rhizomucor pusillus after second stem cell transplantation (SCT) for myelodysplastic syndrome, complicated by multi organ failure, myocardial ischemia and infarction. Zygomycosis is common in immunocompromised patients, especially hematopoietic (HSCT). Mucor species have devastating properties causing ...

Enzymatic synthesis of sugar fatty acid esters were performed in an organic solvent using Immobilized Rhizomucor miehei (RMIM) lipase with sucrose and non-edible rice bran fatty acid as substrates. The maximum conversion of sucrose esters up to 78% obtained when sucrose and non-edible rice bran fatty acid were reacted in molar ratio of 1:8, using n-butanol as a solvent and 1% molecular sieves w...