Background: CDKN2A, encoding two important tumor suppressor proteins p16 and p14, is a tumor suppressor gene. Mutations in this gene and subsequently the defect in p16 and p14 proteins lead to the downregulation of RB1/p53 and cancer malignancy. To identify the structural and functional effects of mutations, various powerful bioinformatics tools are available. The aim of this study is the ident...

Risk management is one of the most important phases of project management and isthe most recently used by many researchers. In this paper, a fuzzy based method wasproposed which identifies different kinds of risks through the project life cycle.Then, the project risk magnitude can be obtained in regards to five factors, namely“severity”, “occurrence”, and “not detection” which form fuzzy FMEA a...

This paper deals with the choice of the risk identification methods in relation to maturity in product design and project processes, product innovation degree and project team. Product development projects involves risk taking, mainly in the product design phase since critical decisions are made with vague, qualitative and often insufficient information. In this context, risk management is fund...

background: up to today, the most complete risk assessment tool for repetitive movements of upper limbs has been the occupational repetitive actions (ocra) method. the index of the analysis is relatively accurate. several risk factors such as repeated motion, force, body condition, additional effective factors and return period can be useful for future preventive measures. the present study eva...