Acute acalculous cholecystitis and acute hemorrhagic cystitis due to Salmonella Typhi are a rare condition. A 24-year-old female patient was admitted to our clinic with abdominal pain, nausea, fever, headache, urinary burning, and bloody urine. Based on clinical, laboratory, and radiological evaluations, the patient was diagnosed with acute acalculous cholecystitis and acute hemorrhagic cystiti...

Aim: To evaluate the anti-bacterial potential of pomegranate against Salmonella typhi. Methodology: Ethanolic extracts of pomegranate's different parts; peel, pericarp and fruit were screened for anti-bacterial activity against Multi-Drug Resistance (MDR) strain (UHS-14) by agar well diffusion method. 6% phenol was used as positive control. Results: The peel extract had the largest inhibitory z...

a multiplex pcr-based assay was developed for detection of salmonella typhi and identification of other salmonella serotypes. three primer-sets were selected from different genomic sequences, malo2-f/malo2-ra primers from invasion gene, parat-s/parat-as as well as tyv-s/tyv-as primers from o-antigen gene cluster of the genus salmonella. this method differentiated salmonella spp., based on size ...

Four murine monoclonal antibodies (MAbs) to Salmonella typhi flagellin were produced. These MAbs did not react with eight other enterobacterial strains tested: Salmonella enteritidis, Salmonella typhimurium, Salmonella paratyphi A, Escherichia coli, Shigella flexneri, Shigella sonnei, Yersinia enterocolitica, and Campylobacter jejuni. All four MAbs cross-reacted with Salmonella muenchen flagell...

In recent years, there has been a significant rise in the prevalence of multidrug resistance Salmonella typhi and salmonella paratyphi in Dhaka city. Patients are most susceptible to infections like typhoid fever. It is therefore a subject of interest to observe the number of incidence and antimicrobial resistant pattern of typhoidal Salmonella in patients in Dhaka city. During February to May ...

Cancer is fueled by deregulation of signaling pathways in control of cellular growth and proliferation. These pathways are also targeted by infectious pathogens en route to establishing infection. Gallbladder carcinoma (GBC) is frequent in the Indian subcontinent, with chronic Salmonella enterica serovar Typhi infection reported as a significant risk factor. However, direct association and caus...

Salmonella enterica subspecies enterica serovar Typhi is a rod-shaped, Gram-negative, facultatively anaerobic bacterium. It belongs to the family Enterobacteriaceae in the class Gammaproteobacteria, and has the capability of residing in the human gallbladder by forming a biofilm and hence causing the person to become a typhoid carrier. Here we present the complete genome of Salmonella enterica ...

Enteric fever prevails as a major public health problem despite the use of antimicrobials due to the emergence of drug resistance. The present study was undertaken to find out the antimicrobial susceptibility pattern of Salmonella isolates from our region. Antimicrobial susceptibility testing for six drugs chloramphenicol (30μg), amoxicillin (10μg), cotrimoxazole (1.25/23.75μg), nalidixic acid ...

Salmonella enterica serovar Typhi, the cause of typhoid fever, is host-adapted to humans and unable to cause disease in mice. Here, we show that S. Typhi can replicate in vivo in nonobese diabetic (NOD)-scid IL2rγ mice engrafted with human hematopoietic stem cells (hu-SRC-SCIDmice) to cause a lethal infectionwith pathological and inflammatory cytokine responses resembling human typhoid. In cont...