Paederus dermatitis is an irritant contact dermatitis due to accidental contact by a beetle belonging to the genus paederus. In this study, clinical efficacies of S. ebulus fruit extract solution in patients affected by paederus dermatitis were evaluated. A randomized double-blind, prospective, placebo-controlled clinical trial was performed in 62 patients with clinical symptoms and sings of de...

In this study we used the chronic (formalin test) and acute (tail flick) pain models of rats for evaluation of probable analgesic and anti-inflammatory effect of Sambucus ebulus (Se) rhizome extract. Sodium salicylate (SS) was used as a positive control. A total of 300 mg/kg of SS (i.p.) had no effect on tail flick latency, while 100 and 200 mg/kg i.p. of extract increased this latency (P < 0.0...

Under the present paper, authors have reposted finding of Sambucus nigra L. as new introduction in medicinal plans in the flora of "Valley of flowers'. Sambucus nigra L. Originally is an European plant and is very important for its medicinal potential, being used in various systems of medicine to cure number of ailments. In natural order Sambucus nigra L. belongs to family caprifoliaceae.

  Pharmacologists believe analgesic and anti-inflammatory drugs such as non-steroidal anti-inflammatory drugs (NSAIDs) and opioid compounds, due to their side-effects and, in some cases, inadequacy, are not always useful. Therefore it seems necessary to search for newer analgesic compounds. In traditional Iranian Medicine, the leaf and rhizome of Sambucus ebulus is used as a topical medication ...