BACKGROUND Proliferation of the intima is an early lesion of saphenous vein graft disease. Early patency rates of radial artery grafts are acceptable, but little is known about their risk of intimal hyperplasia. METHODS AND RESULTS To develop a model of intimal hyperplasia, we incubated human saphenous veins, internal mammary arteries, and radial arteries (n=6, 8, and 10, respectively) in an ...

Acetylstrophanthidin, 1.0 to 10.0 fig/ml, caused contraction of strips of the lateral saphenous vein of the dog in an organ bath at 37°C. The superior mesenteric vein, which exhibited spontaneous activity in the organ bath, responded to acetylstrophanthidin with an almost immediate increase in tension and an increased frequency of contractions; this was followed by a sustained contraction which...

OBJECTIVE The use of foam and liquid sclerotherapy for the treatment of varicose veins and underlying venous reflux is widespread. A novel device, the ClariVein Occlusion Catheter (Vascular Insights LLC, Madison, Conn), has been the subject of several clinical trials in humans. We report the initial histologic results obtained with use of the device in a caprine vein model. METHODS A total of...

Venous ulcer is the most advanced stage of chronic venous insufficiency (CVI). Its prevalence is estimated to be between 1% and 3%. Recent articles have suggested that leg ulcers with reflux in superficial veins can be treated by endovenous laser ablation (EVLA). Endovenous laser ablation of the great and/or short saphenous vein has already become the treatment of choice for varicose vein and c...

V ar ic os e V ei ns Endovenous interventions have transformed the treatment of varicose veins during the past decade. Interest in minimally invasive endovenous thermal ablation of the saphenous vein has substantially increased due to multiple reasons. Both radiofrequency ablation (RFA) and endovenous laser therapy (EVLT) can be performed as an office procedure; they are less invasive and usual...

varicose veins are an extremely common medical condition (present in 5-30% of adults). surgery remains the gold standard of care in patients with varicose veins, however several newer interventions have been recently introduced which need to be evaluated. during the standard surgery it is imperative to demonstrate and ligate the tributaries of the saphenofemoral junction in combination with str...

Background: Presence of reflux in saphenofemoral and saphenopopliteal junctions represents important data for indication of varicose vein surgery. Studies demonstrated that in most patients with chronic venous insufficiency junctions are competent and reflux is present in segments in the course of saphenous veins. Objectives: To identify the probability of different reflux patterns in the saphe...

OBJECTIVE Among the veins used as a graft in myocardial revascularizations and ends, great saphenous vein is the most used. Knowing the presence and location of valves has great importance when evaluating the surgical anatomy of the great saphenous vein. Despite major surgical application and many works involving great saphenous vein, the number of valves present in it from the saphenous hiatus...

BACKGROUND After coronary artery bypass grafting procedures with saphenous vein, there is a protracted elevation of plasma homocysteine and copper. These interact to elicit endothelial dysfunction through promotion of superoxide. It has been suggested that angiogenesis and the formation of a neovasa vasorum is important in mediating vein graft patency. A novel in vitro model of angiogenesis in ...

Saphenous veins were taken for examination: unchanged, varicose with thrombophlebitis and varicose thrombus. The contents of haemoglobin and protein were determined in the homogenate of that material. Only small quantities of haemoglobin were found in walls of unchanged veins. Greater amounts of haemoglobin were observed in walls of varicose veins, especially in walls of varicose veins with thr...