OBJECTIVE To evaluate the cost-effectiveness of the European community-based project '10 000 Steps Ghent', an intervention that resulted in a significant decrease in sedentary time and a significant increase in step counts (896 steps/d) and self-reported walking (66 min/week). DESIGN An age- and gender-dependent Markov model, with a time horizon of 20 years and a cycle length of 1 year, estim...

Multidisciplinary, evidence-based guidelines for quality assurance in colorectal cancer screening and diagnosis have been developed by experts in a project coordinated by the International Agency for Research on Cancer. The full guideline document covers the entire process of population-based screening. It consists of 10 chapters and over 250 recommendations, graded according to the strength of...

In order to solve these problems, we should develop brand-new approaches to analysis and assessment of R&D cost-effectiveness in scientific and production activities as well as innovation activities. In Russia these problems are not attended to properly. There are no more or less significant practical development or theoretical justifications which allow using value approach in management, so t...

Effectiveness and Comparative Effectiveness Reviews, systematic reviews of existing research on the effectiveness, comparative effectiveness, and comparative harms of different health care interventions, are intended to provide relevant evidence to inform real-world health care decisions for patients, providers, and policymakers. In an effort to improve the transparency, consistency, and scient...

BACKGROUND Increasingly, countries have introduced female vaccination against human papillomavirus (HPV), causally linked to several cancers and genital warts, but few have recommended vaccination of boys. Declining vaccine prices and strong evidence of vaccine impact on reducing HPV-related conditions in both women and men prompt countries to reevaluate whether HPV vaccination of boys is warra...

background : this study aimed to assess the effect of new package of interventions on scientific productions rate in shahidbeheshti university of medical sciences.   methods : through a health system research, we extracted policies from the strategic plan of the university and 10 interventions were developed to increase the scientific productions in terms of quality, quantity and commercializat...