Background & Aims: Labor conditions cause stress and anxiety specifically in nulliparous women and hence the chance of a normal vaginal delivery is reduced. According to some studies lavender scent improves mood and reduces stress and anxiety. The purpose of this study was to investigate the effect of lavender scent on anxiety status in nulliparous women and also to determine changes in plasma ...

Suicide is a complex and multifaceted public health issue that has been intensively studied to identify its contributing factors. Serotonin, neurotransmitter essential for affective regulation mood control, linked suicidal propensity. Understanding the relative contribution of serotonin’s genetic versus non-genetic influences development effective preventive measures, given etiology suicide inv...

background: given the importance of the role of depression in predicting the outcome of cardiovascular disorders, current medications for treating depression, particularly selective serotonin reuptake inhibitors (ssris), are taken into  consideration. this study aimed to systematically review the published findings in the use of ssris and the risk for cardiac events. materials and methods: an i...

The effect of endogenous serotonin on long-term potentiation (LTP) in region CAI was studied by blocking 5-HT2 receptors with ketanserin in rat hippocampal slices. Such a block significantly en-hanced long-term potentiation of the CAI population spike induced by high frequency stimulation of the schaffer collateral/ commissural pathway. This implies that serotonin acts on 5-HT2 receptors in CAI...

sleep disturbance, known as insomnia, is a common symptom of many mental illnesses. insomnia is one of the most prevalent sleep disorders characterized by sleep difficulty that affects our life and work safety. several lines of evidence support the primary insomnia as a risk factor/predictor for depression and anxiety disturbances. anxiety disorders and insomnia are common, debilitating and hig...

introduction: 5-ht1a receptor is related with a variety of neuropsychiatric disorders. . in this study a phenolic analogue derived from dway [desmethyl way-100635 (n-(2-(1-(4-(2-methoxyphenyl)piperazinyl)-ethyl))-n-(2-pyridinyl) cyclohexanecarboxamide)] is used to design the desired structure of 5-ht1a receptor imaging agents after labeling with [99mtc (co) 3(h2o) 3] + core via dithiocarbamate ...

objective: electrophysiological studies have identified abnormal oscillatory activities in the cerebral cortex in schizophrenia and mood disorders. biological and pathophysiological evidence suggests specific deficits in serotonin (5-ht) receptor function in schizoaffective disorder (sa), a clinical syndrome with characteristics of both schizophrenia and bipolar disorder. this study investigate...