This paper develops a new mathematical model to study location-routing problem with simultaneous pickup and delivery under the risk of disruption. A remarkable number previous studies have assumed that network components ( e.g. , routes, production factories, depots, etc.) are always available can permanently serve customers. assumption is no longer valid when faces disruptions such as flood, e...

This paper deals with the Vehicle Routing Problem with Simultaneous Pickup and Delivery (VRPSPD). A procedure based on the Iterated Local Search (ILS) metaheuristic that uses the Variable Neighborhood Descent (VND) method for performing the local search is proposed. According to literature, the most successful algorithms for the VRPSPD are pure or hybrid versions of the Tabu Search metaheuristi...

In this work we present a first feasibility study of the ClearPEM technology for simultaneous PET-MR imaging. The mutual electromagnetic interference (EMI) effects between both systems were evaluated on a 7 T magnet by characterizing the response behavior of the ClearPEM detectors and front-end electronics to pulsed RF power and switched magnetic field gradients; and by analyzing the MR system ...

The vehicle routing problem with simultaneous pickup and delivery (VRPSPD) is a well-known combinatorial optimization problem which addresses provided service to a set of customers using a homogeneous fleet of capacitated vehicles. The objective is to minimize the distance traveled. The VRPSPD is an NP-hard combinatorial optimization problem. Therefore, practical large-scale instances of VR...

The vehicle routing problem with simultaneous pickup and delivery (VRPSPD) is a well-known combinatorial optimization problem which addresses provided service to a set of customers using a homogeneous fleet of capacitated vehicles. The objective is to minimize the distance traveled. The VRPSPD is an NP-hard combinatorial optimization problem. Therefore, practical large-scale instances of VR...

In mammals, the oocyte and its surrounding cumulus cells constitute on oocyte cumulus complex (OCC). During ovulation, OCCs are extruded into the peritoneal or bursal cavity, depending on the species, and are then rapidly picked up by the fimbria on the outer surface of the oviductal infundibulum and transported to the ampulla, where fertilization occurs. We developed a method to measure OCC pi...

Interstellar pickup ions are dynamically important in the outer heliosphere where they mass-load and heat the solar wind. Some of these pickup ions are transformed into energetic neutral atoms (ENAs) by charge exchange with the residual cold interstellar gas that is the primary constituent of the outer heliosphere. The most detailed measurements of interstellar pickup ions in the heliosphere ar...

This paper considers a special vehicle routing problem, the two-echelon problem with simultaneous delivery and pickup demands (2E-VRPSDP). The 2EVRPSDP differs from classic transportation problems in two ways. First, freight depot to customers is managed by shipping through intermediate satellites. Second, each customer 2E-VRPSDP may have demands. an extension of (2E-VRP) (VRPSDP). A variable n...