نتایج جستجو برای: smooth muscle cell

تعداد نتایج: 2007746  

Journal: :Renal Failure 2021

A high coronary artery calcification score (CACS) may be associated with mortality in patients undergoing hemodialysis (HD). Recently, effects of iron on vascular smooth muscle cell calcificat...

Journal: :the iranian journal of pharmaceutical research 0
mohammad hossein boskabady mums milad hashemzehi neurogenic inflammation research centre and dept. of physiology, school of medicine, mashhad university of medical sciences, mashhad, iran mohammad reza khazdair pharmaciutical research center and dept. of physiology school of medicine, mashhad university of medical sciences, mashhad, iran vahid reza askari student research committee, faculty of pharmacy, mashhad university of medical sciences, mashhad, iran

the stimulatory effect of the extract of portulaca oleracea (p. olerace) on β-adrenoceptor of tracheal smooth muscle was examined. to examine β-adrenoceptor stimulatory effect, concentration response curve to isoprenaline was obtained in pre-contracted tracheal smooth muscle in the presence of three concentrations of aqueous-ethanolic extract, propranolol and saline. values of ec50 (the effecti...

جعفرزاده, پرستو, عابدین زاده, محمود, قربانی, احمد, محسنی مهران, سید محمد, مولادوست, حسن, نورس فرد, محمدرضا,

Background and purpose: Airway stenosis is one the most dangerous diseases. Anethum graveolens L.(Dill) has anti-spastic effect on smooth muscle. The aim of this study was to investigate the effect of the hydroalcoholic extract of this plant on male rat tracheal smooth muscle contractile activity. Materials and methods: In this experimental study, tracheas of healthy rats were dissected. We in...

2013
Mohammad Afzal Khan

UNLABELLED BACKGROUND Airway inflammation stimulates proliferation of airway smooth muscle cell, which contributes to the development of hyperplasia and hypertrophy of smooth muscle cell. The increase in airway smooth muscle cell mass is believed to be due to an up-regulation of inflammatory mediators in the airway. It is now well recognized that chronic inflammation as well as airway hyper-...

Aref Azar, Helia, Davoudi, Negin, Nabatchian, Fariba,

LOX-1 is a class E scavenger receptor that mediates the uptake of oxLDL by vascular cells. LOX-1 is involved in endothelial dysfunctions, monocyte adhesion, the proliferation, migration, and apoptosis of smooth muscle cells, foam cell formation, platelet activation, as well as plaque instability; all of these events are critical in the pathogenesis of atherosclerosis. These LOX-1-dependent bio...

Journal: :The Journal of biological chemistry 2002
Debi K Swertfeger Guojun Bu David Y Hui

This research was undertaken to identify the cell surface receptor responsible for mediating apolipoprotein E (apoE) inhibition of platelet-derived growth factor (PDGF)-directed smooth muscle cell migration. Initial studies revealed the expression of the low density lipoprotein receptor (LDLR), the LDL receptor-related protein (LRP), the very low density lipoprotein receptor (VLDL), and apoE re...

Journal: :Journal of cell science 1997
C C Yao J Breuss R Pytela R H Kramer

Expression of the alpha7 integrin is developmentally regulated and is thought to be tissue-specific for both skeletal and cardiac muscles. We now report that alpha7 is also strongly and ubiquitously expressed by various types of smooth muscle, including vascular, gastrointestinal and genitourinary smooth muscles. In addition, alpha7 was surface-expressed by a number of smooth muscle cell lines ...

Journal: :The Journal of pharmacology and experimental therapeutics 2011
Mitra Esfandiarei Julia T N Lam Sahar Abdoli Yazdi Amina Kariminia Jorge Navarro Dorado Boris Kuzeljevic Harley T Syyong Kaiji Hu Cornelis van Breemen

In this study, we compared the potencies of diosgenin, a plant-derived sapogenin structurally similar to estrogen and progesterone, on vascular smooth muscle functions ranging from contraction and migration to apoptosis. The effects of diosgenin on vascular smooth muscle cell viability and migration were measured using a primary mouse aortic smooth muscle cell culture. The effects of diosgenin ...

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