Natural selection can produce a correlation between local recombination rates and levels of neutral DNA polymorphism as a consequence of genetic hitchhiking and background selection. Theory suggests that selection at linked sites should affect patterns of neutral variation in partially selfing populations more dramatically than in outcrossing populations. However, empirical investigations of se...

Despite the great potential of single nucleotide polymorphism (SNP) markers in evolutionary studies, in particular for inferring population genetic parameters, SNP analysis has almost exclusively been limited to humans and 'genomic model' organisms, due to the lack of available sequence data in non-model organisms. Here, we describe a rapid and cost effective method to isolate candidate SNPs in...

results the analysis of data for c/t snp showed that the cc genotype is more common in the control group than in the group of patients. in contrast, the frequency of tt as a mutant genotype is more frequent in patients than in uninfected people. in addition, results showed a statistically significant relationship between cc, ct, and tt genotypes in sensitive and resistant groups (p value: < 0.0...

Genetic predisposition without doubt is one of the risk factors cancer initiation. It known that single nucleotide polymorphisms (SNP) genes maintain genome stability, including SNP DNA repair, may contribute to initiation carcinogenesis. Single-nucleotide support repair genes, can Polymorphism excision gene OGG1 causes interest leading scientific groups from various countries. assumed there re...

High-throughput next-generation sequence-based genotyping and single nucleotide polymorphism (SNP) detection opens the door for emerging genomics-based breeding strategies such as genome-wide association analysis and genomic selection. In polyploids, SNP detection is confounded by a highly similar homeologous sequence where a polymorphism between subgenomes must be differentiated from a SNP. We...

Hygienic behavior is a social defense mechanism against parasites and pathogens in honeybees. We studied the genetic basis of hygienic African-derived Apis mellifera by performing RNA sequencing on brains individual honeybee workers observed behavior, order to identify expression changes linked with this behavior. also used transcriptome data search for single nucleotide polymorphism (SNP) vari...

Abstract Chronic inflammation plays an important role in the progression and outcome of chronic kidney disease (CKD). The circulating levels inflammatory biomarkers interleukin 6 (IL6) pentraxin 3 (PTX3) are enhanced CKD patients, associated with higher risk for cardiovascular events, major cause death patients. Our aim was to study how specific polymorphisms IL6 PTX3 encoding genes affect resp...

We performed Bayesian clustering analysis using STRUCTURE software with genotype data on 33,063 commercial single nucleotide polymorphism (SNP) markers in 4,348 Japanese Black fattened steers slaughtered at carcass markets Tokyo, Osaka, Hyogo, Tottori, and Hiroshima prefectures. When the number of assumed clusters was 2, from Hyogo prefecture were clearly separated others. This indicates useful...

Abstract. Ermawati D, Panjono, Bintara S, Hartatik T. 2022. Diversity of partial sequence leptin gene (Exon 3) in crossbred cattle compared to GenBank database. Biodiversitas 23: 5614-5620. Genetic marker method that is often used select Single Polymorphism Nucleotide (SNP). Polymorphisms (SNP) has been found various candidate genes, one which the gene. Leptin a affects reproduction and weight....