O Oeste da Bahia caracteriza-se como uma região marcada pelo agronegócio e pela expansão das novas fronteiras agrícolas; em contrapartida, essa mesma é caracterizada também pelas altas concentrações de terra, sobre as quais emprega-se, neste estudo, o índice Gini (IG), para mensurar esse fenômeno socioeconômico com repercussões socioambientais. Diante disso, este artigo tem objetivo analisar di...

Background Decision-makers have begun to recognize Health-Related Quality of Life (HRQoL) as an important and measurable outcome of healthcare interventions; and HRQoL data is increasingly being used by policy-makers to prioritize health resources. Our objective was to measure HRQoL in a group of Type 2 Diabetes Mellitus (T2DM) patients receiving insulin treatment in Buenos Aires, Argentina.   ...

Secondary B cell repertoire diversification occurs by somatic hypermutation (SHM) in germinal centers following Ag stimulation. In SHM, activation-induced cytidine deaminase mutates the V region of the Ig genes to increase the affinity of Abs. Although SHM acts primarily at Ig loci, low levels of off-target mutation can result in oncogenic DNA damage, illustrating the importance of understandin...

Protein A and protein G are two well-defined immunoglobulin (Ig)-binding proteins (IBPs), which show affinity for specific sites on Ig of mammalian hosts. Protein A and protein G contained several highly homologous IgG-binding domains which had been demonstrated to have function to bind to IgG. Whether combinations of Ig-binding domains of various IBPs could produce useful novel binding propert...

s ig n a n d Im p le m e n ta tio n o f th e S c a la b le M u ltic a s t B a la n c e d G a m m a (B G) S w itc h Ab s tr a c t — T h is p a p e r p r e s e n ts th e d e s ig n a n d im p le m e n ta tio n o f a n e w m u ltic a s t s w itc h fo r b r o a d b a n d c o m m u n ic a tio n s. U s in g d is tr ib u te d c o n tr o l a n d m o d u la r d e s ig n , th e m u ltic a s t B a la n c ...

Induction of a T cell mediated immune response is critical for the eradication of viral infections and tumours. Soluble peptide-loaded major histocompatibility complex-Ig ((pep-)MHC-Ig) have been shown to bind their cognate ligands, T cell receptor, with high affinity, and are successfully used to visualize antigen-specific T cells. Furthermore, immobilized (pep-)MHC-Ig can activate and expand ...

An incidence of a graph G is a pair (v, e) where v is a vertex of G and e an edge incident to v. Two incidences (v, e) and (w, f) are adjacent whenever v = w, or e = f , or vw = e or f . The incidence coloring game [S.D. Andres, The incidence game chromatic number, Discrete Appl. Math. 157 (2009), 1980–1987] is a variation of the ordinary coloring game where the two players, Alice and Bob, alte...

Giriş: Çölyak hastalığı (ÇH) gluten protenine karşı T hücre aracılığı ile gelişen besin intoleransıdır. Gluten çocuklarda en sık alerjenlerinden biri olan buğdayın da başlıca proteinlerindendir. Besin alerjileri immunglobulin-E aracılı, aracılı veya karma reaksiyon gelişebilir. Hücre alerjik reaksiyonlarda deri yama testi yol göstericidir. Bu çalışmada ÇH'da alerjisi varlığının araştırılması am...