نتایج جستجو برای: stage expression
تعداد نتایج: 1187428 فیلتر نتایج به سال:
Background: Vascular calcification is an important stage in atherosclerosis. During this stage, vascular smooth muscle cells (VSMC) synthesize many osteogenic factors such as osteonectin (encoded by SPARC). Oxidative stress plays a critical role in atherosclerosis progression, and its accumulation in the vascular wall stimulates the development of atherosclerosis and vascular calcification. The...
introduction: colorectal carcinoma is a main health problem in many countries and the third common cancer in iran. this malignancy at present is the most curable carcinoma of gastrointestinal tract. variation in the expression of the proteins produced by p53, p21, p16, e-cadherin, and β-catenin genes have been noted in this malignancy and may be important in the prognosis and therapeutic respon...
Background: Polycystic ovary syndrome (PCOS) is a frustrating experience for women, considered as a complex challenge for researchers and clinicians. Despite the enormous effort to define the cause of PCOS, the etiology and pathogenesis still remain unclear. Oocyte quality is reflected in the oocyte’s intrinsic developmental potential. Studies have shown that the follicular development is disru...
Introduction: There are few studies regarding the field of catalase gene expression, antioxidant and oxidant response in trained women, thus these markers’ levels have not been designated within Iranian trained women specially in regard to incremental exercise. Therefore, this study aimed to investigate Catalase enzyme Gene expression and oxidant levels in trained women. Methods: A repeated me...
Phenylalanine amonia-lyase (PAL) is one of the most important enzymes that plays a key role in regulationof phenylpropanoid production in plants. It catalyzes the first step of the phenylpropanoid pathway in whichL-phenylalanine is deaminated to trans-cinnamic acid. This step is significant for metabolic engineering andhyper-expression of the major phenylpropanoid, methyl chav...
The Serial Analysis of Gene Expression (SAGE) method, described in 1995 by Velculescu et al ., represents a powerful means to compare gene expression between two mRNA populations. An improvement to SAGE that removes contaminating linker molecules, which compromise the efficiency of the method, has been developed. This modification utilises biotinylated PCR primers, which generate biotinylated l...
Background and Objectives: RCC is one of the most common genitourinary cancers. Accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. P53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle ar...
در این مطالعه اثر داروهای آدرنرژیک بر بروز (expression) و گسترش (development) تولرانس به اثرات بی دردی مرفین در فرمالین تست بررسی شده است. در نهایت چنین نتیجه گیری می شود که مکانیسمهای شa2 آدرنوسپتور ممکن است در بی دردی و تولرانس ناشی از مرفین دخیل باشند.
چکیده مقدمه: مالتیپل میلوما حاکی از تکثیر بدخیم پلاسماسل هایی است که از کلون منفرد مشتق شده اند. تومور، محصولات آن و پاسخ به آن منجر به تعدادی از اختلالات عملکرد ارگانی و علائمی از درد یا شکستگی استخوانی، نارسایی کلیه، افزایش استعداد ابتلا به عفونت، آنمی، هیپرکلسمی و گاهاً اختلالات انعقادی، علائم نورولوژیک و تظاهرات عروقی هیپرویسکوزیته می گردند. علت ایجاد میلوم ناشناخته است. علل اصلی مرگ میلوم ...
background and objectives: rcc is one of the most common genitourinary cancers. accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. p53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle arrests after dna damage and apoptosis. presence of mutated p53 protein in tumors has been rel...
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