Iron can contribute to the pathogenesis and progression of multiple sclerosis (MS) due to its accumulation in the human brain. We focus on the thalamus as an information transmitter between various subcortical and cortical areas. Thalamic iron seems to follow different rules than iron in other deep gray matter structures and its relation to the clinical outcomes of MS is still indistinct. In ou...

We develop a new statistic for testing the equality of two multivariate mean vectors. A scaled chi-squared distribution is proposed as an approximating null distribution. Because the test statistic is based on componentwise statistics, it has the advantage over Hotelling's T2 test of being applicable to the case where the dimension of an observation exceeds the number of observations. An appeal...

We derive a general formalism with which it is possible to obtain the time (τ) dependence of the echo size for a spin in a stochastic field environment. Our model is based on “strong collisions”. We examine in detail three cases where: (I) the local field is ±ω0, (II) the field distribution is continuous and has a finite second moment, and (III) the distribution is Lorentzian. The first two cas...

Cartilage is responsive to the loading imposed during cyclic routine activities. However, the local relation between cartilage in terms of thickness distribution and biochemical composition and the local contact pressure during walking has not been established. The objective of this study was to evaluate the relation between cartilage thickness, proteoglycan and collagen concentration in the kn...

Pore network models are used to relate fundamental pore structure parameters (pore body and pore throat size distributions) to the distribution of water at the pore level and the decay of proton magnetization under conditions of primary drainage in water-wet rocks. The simulations reveal conditions under which diffusive coupling between pores has a significant effect on the decay spectra and pr...

Background Cardiovascular magnetic resonance (CMR) can provide a non-invasive means of measuring the amount of tissue iron. The iron results in shortening of proton relaxation times and both CMR T2* and T2 have been validated as non-invasive means for assessment of myocardial iron overload. (1,2,3,4). We have reported that a T2* value below 20ms represents iron overload in the heart (5). This c...

PURPOSE To determine the spatial variation of in vivo cartilage T2 in young asymptomatic adults. MATERIALS AND METHODS Quantitative T2 maps of seven asymptomatic young male adults and one male volunteer with a history of previous intraarticular chondroid fragments were calculated by using a multiecho, spin-echo magnetic resonance imaging sequence at 3.0 T. The T2 maps were bilinearly interpol...

one of the main strategy for controlling salt-affected soils is to implement proper tillage method. a field experiments was conducted to determine the effect of different tillage methods on salt distribution and wheat yield in saline-sodic soil. the experiment was laid out according to randomized complete block design with three replications. treatments were studied in the experiment including ...