The three small Maf proteins, MafF, MafG and MafK, have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response. Here we report the constitutive expression of mafF, mafG and mafK in six human cell lines derived from various tissues (HepG2, IMR-32, K-562, HEK-293, RD and A549). The expression patterns of mafF, mafG and ma...

In the absence of extracellular Ca2+, extensive Ca2+ release from the platelet intracellular stores [monitored as an increase of intracellular Ca2+ concentration ([Ca2+]i)] is produced by the combined action of the endomembrane Ca(2+)-ATPase inhibitor thapsigargin and 2 nM ionomycin. The titration of Ca2+ unloading with thapsigargin (plus ionomycin) shows that a substantial fraction of the stor...

The transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) coordinates expression of genes required for free radical scavenging, detoxification of xenobiotics, and maintenance of redox potential. Previously, activation of this pleiotropic response was neuroprotective in cell culture models that simulate components of stroke damage. However, the role of Nrf2 in limiting stroke d...

Three extraction parameters including time, material to solvent ratio, and temperature for the yield of Phyllanthus urinaria polysaccharides were optimized by response surface methodology. The results revealed that optimal process was time 5.3 h, 93 °C, ratio 1:47 g/mL, under which polysaccharide 6.40%; three had significant effect on yield, influence greatest lowest. antioxidant activity test ...

TBHQ has already been evaluated by the former Scientific Committee on Food (SCF) which concluded in 1987 that there was still a need for additional data. The SCF requested an adequate carcinogenicity study and an in vivo mutagenicity study of germ cell effects. At that time, the SCF was of the opinion that TBHQ was not acceptable for use as an antioxidant to food and did not establish an accept...

Electrochemical determination of tert-butylhydroquinone (TBHQ) is vital to food safety due negative health effects; however, bare electrode traditional electrochemical sensors generally has a narrow linear range and low sensitivity, limiting their practical application. Accordingly, the nano-architecture fabricated with N-doped TiO2–carbon nano-composites (TiO2/NC) prepared by thermolysis NH2 f...

Biodiesel is one of alternative energies that can be used to overcome problem caused by limited amount fossil fuels reserved. made from rubber seed oil has high potencies in Indonesia. The availability quite much with more than 3-million-hectare plantation area. production biodiesel been carried out several researchers using various methods. Therefore, this study was conducted as a review obtai...

Green tea ( Camellia sinensis (L.) Kuntze) is a potent natural ingredient with flavonoid content that can be used as an antioxidant and anti-aging for skincare products. The formula containing green extract usually formulated oil in water emulsion or cream. active components of are catechins which characterized less stable against oxidation. Therefore, it needed to add other antioxidants such B...

considering that the involvement of oxidative stress has been implicated in the toxicity of organophosphate insecticides, the objective of the present study was to investigate antioxidants and oxidative stress markers in the liver and kidney of wistar rats treated with chronic doses of diazinon. in addition, the effect of tert-butylhydroquinone (tbhq), a food-additive antioxidant, on attenuatio...