OBJECTIVE The purpose of this study was to investigate if an octadecyl (18C) minicolumn could be applied successfully for quality control of 99mTc exametazime (HMPAO). METHODS The 18C column system using saline eluent was validated against the Whatman 17 method in calculating the percent radiochemical purity of 99mTc-HMPAO. The behavior of 99mTc-pertechnetate (99mTc04-) and hydrolyzed-reduced...

  Tc-99m pertechnetate scintigraphy is the modality of choice for diagnosis of Meckel's diverticulum. Interpretation of Meckel's scan identifies a focal area of radiopharmaceutical uptake in the anterior abdomen similar to normal gastric mucosa. The activity must be of the same pattern and intensity as gastric uptake. We present a 13-year-old patient with gastrointest...

Objective(s): To review the findings of the patients with Sjögren’s syndrome (SS) having technetium-99m-pertechnetate (99mTc-pertechnetate) and gallium-67 citrate (Ga-67) salivary gland scintigraphy in the past eight years.Methods: The patients with SS, who were referred to our department for salivary gland scintigraphy during January 2008-December 2015 were studied using both 99mTc-pertechneta...

UNLABELLED For noninvasive monitoring of cellular status by dual reporters, a dual membrane protein reporter system was developed and its in vivo applicability was examined. Human sodium iodide symporter (hNIS) and mutant dopamine D(2) receptor (D(2)R) transgenes were chosen considering their complementarity. METHODS pIRES-hNIS/D(2)R containing NIS and D(2)R linked with an internal ribosomal ...

Due to the high variance in available protocols on iodide-131 ((131)I) ablation in rodents, we set out to establish an effective method to generate a thyroid-ablated mouse model that allows the application of the sodium iodide symporter (NIS) as a reporter gene without interference with thyroidal NIS. We tested a range of (131)I doses with and without prestimulation of thyroidal radioiodide upt...

The aim of this in vitro study was to evaluate the possible interference of a Nectandra membranacea extract (i) on the labeling of blood cells (BC), (ii) on the labeling process of BC and plasma (P) proteins with technetium-99m (Tc-99m) and (iii) on the morphology of red blood cells (RBC). Blood samples were incubated with a Nectandra membranacea crude extract, stannous chloride, Tc99m (sodium ...

DMSA (meso-2,3-dimercaptosuccinic acid) adalah suatu senyawa dengan gugus sulfhydryl yang mampu berikatan secara chelation berbagai logam berat. Awalnya dimanfaatkan sebagai antidotum keracunan berat, namun seiring berjalannya ilmu pengetahuan, berhasil ditandai menggunakan Tc-99m Pertechnetate dan dimaanfaatkan luas dalam bidang kedokteran nuklir. scan telah digunakan nefrourologi, terutama un...