Nitric oxide has been shown to be an inhibitory neurotransmitter in the mammalian colon, although its role in colonic transit remains unclear. We investigated the effect of the nitric oxide biosynthesis inhibitor NG -nitro-l-arginine methyl ester (l-NAME) on colonic transit in conscious rats. Colonic transit was determined by calculating the geometric center of the distribution of radiochromium...

introduction: functional constipation is one of the most common gastrointestinal symptoms which could affect patients’ quality of life. the colonic transit time test could be used for determining functional constipation subtypes. the aim of our study was to determine the abnormalities of the subtypes of functional constipation using ctt. methods and materials: this cross-sectional study was per...

To ensure an adequate organ mass, the daughters of stem cells progress through a transit-amplifying phase displaying rapid cell division cycles before differentiating. Here, we show that Arabidopsis thaliana microRNA miR396 regulates the transition of root stem cells into transit-amplifying cells by interacting with GROWTH-REGULATING FACTORs (GRFs). The GRFs are expressed in transit-amplifying ...

Due to the huge vehicle-track-under rail foundation-earth coupling system, prediction and evaluation of environmental vibration caused by transit are subject analysis efficiency for a long time. Whether it is test or theoretical simulation, research object often limited specific sensitive points. However, scientific accurate urban planning requires that global. Referring noise map technology, t...

Currently, over forty transiting planets have been discovered by ground-based photometric surveys, and space-based missions like Kepler and CoRoT are expected to detect hundreds more. Follow-up photometric observations from the ground will play an important role in constraining both orbital and physical parameters for newly discovered planets, especially those with small radii (Rp . 4 R⊕) and/o...

Susceptibility to postoperative ileus following abdominal surgery increases with advancing age. The mechanisms underlying this phenomenon are unknown. This study compares functional and molecular endpoints between young-adult (2 mo old), middle-aged (15 mo old), and elderly mice (26-30 mo old) to identify potential mechanisms. Susceptibility to ileus was assessed by measuring gastrointestinal t...

Nowadays, traffic management policy in metropolitans is focused on increasing the share of public transit. The limitation of supply and slowing growth of road infrastructures have provided congestion for users who choose personal cars. Therefore, applying demand management policies which decrease the utility of personal cars and increase the tendency to public transit can be very important. Con...

California Partners for Advanced Transit and Highways, University of California at Berkeley (1357 S.46th Street, Bldg. 452, Richmond, CA 94804, USA, +1 510-665-3515, [email protected], [email protected], [email protected]) Center for Environmental Research and Technology, University of California at Riverside (1084 Columbia Ave, Riverside, CA 92507, USA, +1 951-781-5791 kanok@cert....

The Americans with Disabilities Act of 1990 (ADA) transportation requirements ushered in a new era of public transportation accessibility for persons with disabilities. This groundbreaking civil rights initiative has given persons with disabilities the same mobility opportunities as others by requiring accessible fixed route transportation, as well as complementary paratransit services for indi...