The microaerophilic protist parasite is occurring globally Trichomonas vaginalis and causes infections in the urogenital tract in humans, a condition termed trichomoniasis. In fact, trichomoniasis is the most prevalent non-viral sexually transmitted disease with more than 250 million people infected every year. Although trichomoniasis is not life threatening in itself, it can be debilitating an...

Background: Trichomonas vaginalis is a common pathogen with worldwide distribution. It is estimated that worldwide 180 million people are infected annually. Trichomoniasis is associated with vaginitis, cervicitis, low birth weight, and preterm delivery in pregnant women in addition, it is a cofactor in HIV transmission. Diagnosis of disease is traditionally depends on the microscopic observatio...

Background: Trichomoniasis is a worldwide sexually transmitted disease (STD), and is associated with important public health problems, including enhancement of HIV transmission. The prevalence of the parasite, Trichomonas vaginalis, depends on host factors such as age, sexual activity, number of sexual partners and sexual behavior. The aim of the study was to evaluate the prevalence of trichomo...

results a total of 600 women were screened for t. vaginalis infection and this infection was diagnosed in 9 (1.5%) and 13 cases (2.1%) using the wet mount and culture methods, respectively. the age and husband occupation were significantly associated with an increased risk of trichomoniasis in the infected cases (p < 0.05 and p < 0.001, respectively); other variables, including the patients' oc...

Trichomoniasis is one of the most common sexually transmitted diseases, with around 120 million world-wide suffering from Trichomonas vaginalis-induced vaginitis every year. Although trichomoniasis can be treated with metronidazole, the prevalence of metronidazole-resistant T. vaginalis seems to be increasing. Since the percentage of AT base pairs in T. vaginalis DNA (71%) is very much higher t...

Metronidazole (MDZ) and related 5-nitroimidazoles are the recommended drugs for treatment of trichomoniasis, a sexually transmitted disease caused by the protozoan parasite Trichomonas vaginalis. However, novel treatment options are needed, as recent reports have claimed resistance to these drugs in T. vaginalis isolates. In this study, we analyzed for the first time the in vitro effects of the...

Trichomoniasis is a sexually transmitted disease due to infection with Trichomonas vaginalis, and it can cause serious consequences for women's health. To study the virulence factors of this pathogen, T. vaginalis surface proteins were investigated using polyclonal antibodies specific to the membrane fractions of T. vaginalis. The T. vaginalis expression library was constructed by cloning the c...

Introduction: Trichomoniasis, caused by the protozoan parasite, Trichomonas vaginalis, is a common but curable sexually transmitted disease (STD) affecting millions around the world. It can cause a variety of symptoms in women, namely, vaginal discharge, blood spotting, itching, redness and pain during sexual intercourse or urination. Trichomoniasis carries with it complications such as cervici...

For more than a century following its initial description in 1836, Trichomonas vaginalis was considered to be either a harmless vaginal colonizer or simply a minor nuisance [1]. This view may have been sustained by the observation that women with trichomoniasis vaginalis were usually either asymptomatic or had only mild symptoms. More recently, it has been recognized that T. vaginalis infection...