PURPOSE The purpose of this study was to develop a novel and continuous method for preparing a nanosized particle of drug crystals and to characterize its properties. MATERIALS AND METHODS A new apparatus was introduced to crystallize nanosized drug crystals of amitriptyline hydrochloride as a model drug. The samples were prepared in the pure state by ultrasonic spray, and elaborated depositi...

asphaltene precipitation and deposition is a serious problem in many iranian fields. the deposited asphaltene results in partial or total blockage of the wellbore and wellstring reducing or completely seizing oil production. this paper studies the asphaltene problem and mitigation methods in wellstring systematically. it presents new approach based on the combination of thermodynamic modeling o...

one of the great challenges in the processing of materials using equal channel angular pressing (ecap) is the high forming forces required to produce large shear deformation in the material. researchers show that the friction forces between the die and the sample constitute a great part of the total forming forces. recently, ultrasonic vibrations are successfully implemented into the ecap proce...

ultrasonic assisted drilling (usd) is new technique to drill difficult to machine materials. in this method, tool or workpiece vibrates with amplitude of few microns in addition to conventional drill bite rotation. in this experimental research, the bone was drilled both conventionally and using uad, then the thrust was measured in two methods at feed rates of 50, 75 and 125 mm/s and 500, 710 a...

the perovskite-structured la2cuo4 nanoparticles (lco nps) have been synthesized via an ultrasonic-assisted co-precipitation route using octanoic acidas organic surfactant, and the phase composition, morphology, lattice parameters and size of nanoparticles  are characterized through fourier transform infrared spectroscopy (ft-ir), x-ray diffraction (xrd), scanning electron microscopy (sem) and t...

in this work, boehmite sol was prepared by a previously applied and validated method; hydrolysis of aluminum chloride hexa-hydrate. in order to obtain precise results, the effect of ph after adding precipitating agent, aging time, peptizing temperature and ultrasonic vibration time on the crystallite size of final precipitate were investigated in a narrow range. the preparation conditions appli...

Microwave-assisted and ultrasound-assisted extraction assays were used to isolate total flavonoids (TF) from Osmanthus fragrans flowers. The effects of the solid-liquid ratio, ethanol concentration, microwave power, microwave extraction time, ultrasonic power and ultrasonic extraction time on the yield of TF were studied. A sequential combination of microwave- and ultrasound-assisted extraction...

Ultrasonic energy was applied to assist the wood vacuum drying process. At a drying temperature of 60°C, the absolute pressure was either 0.05 MPa or 0.08 MPa; the ultrasonic power and frequency were 100 W and 28 kHz, respectively. The results showed that the effective water diffusivity of the specimens dried by the ultrasonic assisted vacuum drying at 0.05 MPa or 0.08 MPa were higher than that...

The influence of precipitation of intermetallics on changes in Young’s modulus of nickel and zirconium base alloys has been discussed in this paper. This study indicates that the change in the modulus due to thermal ageing in these alloys is essentially governed by the change in the modulus of the matrix due to removal of precipitation forming elements. 1.0 Introduction Mechanical properties in...