Invasive mechanical ventilation is a life-saving procedure which is largely used in neonatal intensive care units, particularly in very premature newborn infants. However, this essential treatment may increase mortality and cause substantial morbidity, including lung or airway injuries, unplanned extubations, adverse hemodynamic effects, analgosedative dependency and severe infectious complicat...

Two inspiratory times (0.5 and 1.0 seconds) were compared when weaning infants from mechanical ventilation. The shorter inspiratory time was associated with significant increases in minute volume and reduction in active expiration.

sor, associate dean for research, and director, Center for Nursing Research, University of Texas, School of Nursing, at Houston. Hemodynamic Stability Patients’ responses to both mechanical and spontaneous ventilation vary according to myocardial function and reserve capacity. Cardiac failure, which may not be apparent when a patient is receiving mechanical ventilation, can be exacerbated with ...

INTRODUCTION Echocardiographic, electrocardiographic and other cardiorespiratory variables can change during weaning from mechanical ventilation. OBJECTIVES To analyze changes in cardiac function, using Doppler echocardiogram, in critical patients during weaning from mechanical ventilation, using two different weaning methods: pressure support ventilation and T-tube; and comparing patient sub...

AIM To compare T-tube and pressure support ventilation (PSV) as two methods of weaning patients from mechanical ventilation. METHODS A randomized prospective study included 260 patients who received mechanical ventilation for more than 48 h, and who were admitted to the intensive care unit (ICU) at Dr. Josip Bencevic General Hospital in Slavonski Brod, between August 1999 and October 2000. Af...

Searching The following databases were searched from 1971 to 1998 (the search strategies used were provided in the report): MEDLINE, EMBASE, HealthSTAR, CINAHL, the Cochrane Controlled Trials Register and the Cochrane Database of Systematic Reviews. The authors also examined reference lists, handsearched Respiratory Care (from 1997 to 1999), and searched their personal files. The authors did no...

The use of predictive parameters for weaning from mechanical ventilation is a rather polemic topic, and the results of studies on this topic are divergent. Regardless of the use of these predictive parameters, the spontaneous breathing trial (SBT) is recommended. The objective of the present study was to review the utility of predictive parameters for weaning in adults. To that end, we searched...

Weaning covers the entire process of liberating the patient from mechanical support and from the endotracheal tube. Many controversial questions remain concerning the best methods for conducting this process. An International Consensus Conference was held in April 2005 to provide recommendations regarding the management of this process. An 11-member international jury answered five pre-defined ...

About 20% to 30% of patients are difficult to wean from invasive mechanical ventilation. The pathophysiology of difficult weaning is complex. Accordingly, determining the reason for difficult weaning and subsequently developing a treatment strategy require a dedicated clinician with in-depth knowledge of the pathophysiology of weaning failure. This review presents a structural framework ('ABCDE...