introduction: spreading depression (sd) is a propagating wave of depolarization followed by depression of the neuroglial activities and can modulate extracellular dopamine concentrations in the neocortex. it has been shown that the dopaminergic system plays a role in migraine. sd has been suggested as a critical phenomenon in the pathophysiology of migraine. the aim of this study was to investi...

background: endometrial secretion analysis is a non-invasive and promising method in evaluation of endometrial receptivity. objective: the aim of the present study was to assess the relationship between the success rate of ivf procedures and some endometrial secretion cytokines, including interleukin-1β (il-1β), tumor necrosis factor (tnf-α), interferon gamma-induced protein 10 (ip-10), and mon...

Objective: The purpose of the current study was to investigate the in vivo (analgesic, antidiarrheal, neurological, and cytotoxic) and in vitro (antioxidant, antimicrobial, thrombolytic and anthelmintic) activity of different fractions of methanolic extract of Momordica charantia. Materials and Methods: The antioxidant property ...

Background: This study intends to present the role of rescue in vitro maturation (IVM) in polycystic ovarian syndrome(PCOS) patients undergoing in vitro fertilization (IVF) treatment who have inappropriate responses to ovarianstimulation.Materials and Methods: This was a retrospective case series study of five PCOS patients undergoing IVF treatmentconsidered for cycle ca...

callus and suspension cultures of lavandula angustifolia mill. (lamiaceae) were established and the effect of different culture media on growth rate was investigated. terpenoids added to suspension culture to investigate their biotrans-formation. all samples were analyzed by gas chromatography (gc) and gc-mass spectroscopy (ms). octan-1-ol, citronellol, linalool, borneol and geraniol were biotr...

background cutaneous leishmaniasis (cl) is an endemic disease in developing countries. although pentamidine orantimonite (glucantime) has been recommended for cutaneous leishmaniasis treatment by the world health organization, there are some concerns too such as high cost, side effects, need for frequent injections, and restricted efficacy. therefore, different methods have been used for cl tre...

nanotechnology is a rapidly growing field having potential applications in many areas. nanoparticles (nps) have been studied for cell toxicity, immunotoxicity, and genotoxicity. tetrazolium-based assays such as mtt, mts, and wst-1 are used to determine cell viability. cell inflammatory response induced by nps is checked by measuring inflammatory biomarkers, such as il-8, il-6, and tumor necrosi...