To investigate the relative importance of each of the ribose 3'-hydroxyl groups of 2-5A (ppp5' A2'p5'A2'-p5' A) in determining binding to and activation of the 2-5A-dependent endonuclease (RNase L), the 3'-hydroxyl functionality of each adenosine moiety of 2-5A trimer triphosphate was sequentially replaced by hydrogen. The analog in which the 5'-terminal adenosine was replaced by 3'-deoxyadenos...

OBJECTIVES Matrix metalloproteinase is responsible for ventricular remodeling after acute myocardial infarction (MI). The purpose of the present study was to determine whether the matrix metalloproteinase 3 (MMP-3) polymorphism and its level predict morbidity after acute MI (AMI). METHODS We studied 112 patients with AMI and 140 controls. All patients were followed for AMI complications durin...

in this paper we report synthesis of fe2tio5-5a zeolite (z5a) nanocomposites with 5%, 10% and 20% weight percent of fe2tio5 in 5a zeolite in stearic acid media after calcination of the gel samples obtained at 600-900°c for 2 hrs. the powder x-ray diffraction (xrd) patterns have been used for characterization of the prepared samples. the scanning electron microscopy (sem) images and x-ray energy...

background: matrix metalloproteinases comprise a family of enzyme degrade components of extra cellular matrix. there are single nucleotide polymorphisms in the promoter regions of several genes with ability to influence cancer susceptibility. the aim of this study was to analyze association between mmp 3 promoter polymorphisms and colorectal cancer occurrence and progression. materials and meth...