BACKGROUND We longitudinally assessed predictors of insulin resistance (IR) change among HIV-uninfected and HIV-infected (ART-initiators and ART-non-initiators) Rwandan women. METHODOLOGY HIV-infected (HIV+) and uninfected (HIV-) women provided demographic and clinical measures: age, body mass index (BMI) in Kg/(height in meters)2, Fat-Mass (FMI) and Fat-Free-Mass (FFMI) index, fasting serum ...

BackgroundImpaired insulin sensitivity could be an intermediate step that links exposure to air pollution the development of type 2 diabetes. However, longitudinal associations with remain unclear. Our study investigated long-term degree and rate change sensitivity.MethodsIn this study, we analysed data from Cooperative Health Research in Region Augsburg (KORA) cohort Augsburg, Germany, which r...

Our aim was to assess the impact of increase in homeostasis model assessment of insulin resistance (HOMA-IR) on the development of type 2 diabetes in Japanese individuals with impaired insulin secretion (IIS). This study included 2,209 participants aged 30-69 without diabetes at baseline who underwent comprehensive medical check-ups between April 2006 and March 2007 at Saku Central Hospital. Pa...

Methods Patients (pts) from TENDER were included if baseline and wk 6 fasting insulin were measured. Glucocorticoid tapering was not permitted until wk 6. Insulin sensitivity was quantified using the homeostatic model of insulin resistance (HOMA-IR). Pts were classified as having IR if their HOMA-IR was ≥2.2 U. Change in HOMA-IR after 6 wks was assessed using paired t-test. Baseline association...

Glucocorticoids (GCs) are well known to induce insulin resistance. However, the effect of GCs on insulin secretion has not been well characterized under physiological conditions in human. We here evaluated the effect of GCs on insulin secretion/ß-cell function precisely in a physiological condition. A population-based study of 1,071 Japanese individuals enrolled in the 2014 Iwaki study (390 men...

4.3. (i) Since HomA(A (I),M) ∼= M (I) for a set I and ⊕ is exact, it is clear that HomA(A (I),−) is exact, i.e. A(I) is projective. (ii) “Only if” part: Let A(P ) = ⊕ p∈P Ap be the free A-module indexed by P and ψ : A (P ) → p be the A-homomorphism such that ψ(1p) = p. Then ψ is surjective. If P is projective, then ψ has a section, i.e. an A-homomorphism φ : P → A(P ) such that ψ ◦ φ = idP . Th...