1Department of Oncology, Division of Hematologic Malignancies, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD; 2Department of Leukemia, University of Texas M. D. Anderson Cancer Center, Houston; 3Division of Hematology/Oncology, Weill Medical College of Cornell Medical University and New York Presbyterian Hospital, NY; 4Kyowa Pharmaceutical, Princeton, NJ; and 5Clinic...

We have examined the ability of KW-6002, an adenosine A2a antagonist, to modulate the dyskinetic effects of L-DOPA in 6-hydroxydopamine-lesioned rats. In animals rendered dyskinetic by a previous course of L-DOPA treatment, KW-6002 did not elicit any abnormal involuntary movements on its own, but failed to reduce the severity of dyskinesia when coadministered with L-DOPA. A second experiment wa...

A contactless power transfer system for charging electric vehicles requires a high efficiency, a large air gap, and a good tolerance to lateral misalignment and needs to be compact and lightweight. A double-sided winding 10 kW transformer based on a 1.5 kW H-shaped core transformer was developed for a rapid charger. Even though the transformer capacity was increased, the dimensions of the 10 kW...

Using various models of acute renal failure (ARF) in rats, the diuretic effects of 8-(noradamantan-3-yl)-1,3-dipropylxanthine (KW-3902), a novel adenosine A1-receptor antagonist (0.01 and 0.1 mg/kg, p.o.), were determined and compared with those of furosemide (30 mg/kg, p.o.) and trichlormethiazide (TCM; 1 mg/kg, p.o.). In cisplatin-induced ARF rats, KW-3902 and TCM, but not furosemide, increas...

These Interior permanent magnet machines using integral slot windings or non-overlapping concentrated windings are designed for traction applications. Four direct drive traction motors are analyzed: two 25 kW motors and two 100 kW motors at rated speed of 1000 min. Analytical computations are verified by finite element analysis utilizing Cedrat’s Flux2D. Concentrated tooth coil winding machines...

Chronic pancreatitis can be a debilitating disease. Resection for complicated disease and in those patients with intractable pain is a major component of therapy. There are potentially important physiological advantages with the pylorus preserving Kausch-Whipple (P-KW) compared to the standard Kausch-Whipple (KW) resection but further prospective studies are required to show this unequivocally....