The prevalence of class D extended-spectrum oxacillinases (ES-OXAs) in ceftazidime-resistant strains of Pseudomonas aeruginosa is often underestimated by double-disk synergy tests (DDST) using clavulanate. A DDST with a customized distance between a disk of ceftazidime or cefepime and inhibitors (clavulanate and imipenem) detected 14 out of 15 different ES-OXAs.

The paper presents experimental results for the detection of related video streams (views) of multi camera system using MPEG−7 visual signature tools. This detection can be used for identification of video streams stored in video repositories which constitute the same multi camera recording set. Two signature tools have been investigated: Image Signature descriptor and Video Signature descripto...

The CBM muon detection system (MuCh) was optimized for nucleus-nucleus collisions at SIS300 beam energies (see [1]). We have investigated the possibility to simplify the setup for measurements of J/ψ mesons in protonnucleus collisions at SIS100 beam energies. Therefore, the performance of the muon detection system has been studied as function of the number of the detector stations for J/ψ measu...

The strong interaction between streptavidin (SA) and biotin is widely utilized in biotechnological applications. A SA variant, monovalent SA, was developed with a single and high affinity biotin-binding site within the intact tetramer. However, its structural characterization remains undetermined. Here, we seek to determine the crystal structure of monovalent SA at 1.7-Å resolution. We show tha...

Strategic alliances are commonplace in the high-technology sector. Biotechnology is a context in which this organizational arrangement has been particularly signi cant; hundreds of biotech alliances are established each year and these deals have become the primary source of nancing for the young rms in the industry. We posit that the stock of prior alliances between participants in the biotech ...

Introduction In December 2003 GSI was given the first step of approval by the Hesse Ministry for environment to build the new international accelerator facility for beams of ions and antiprotons [1]. This approval was passed after the assessment by the radiation protection experts TÜV [2]. In order to meet the requirements to build the facilities for the FAIR project [3] shielding calculations ...

ence is sufficient to disrupt the nucleolar structure.9 Similarly, the anticancer peptide CIGB-300 leads to nucleolar disassembly and apoptosis, most likely through its capability to bind NPM1.10 Because AML cells carrying the NPM1 mutation are depleted of wild-type NPM1 protein in their nucleolar pool (because of haploinsufficiency and cytoplasmic dislocation through formation of heterodimers ...

In order to increase the slow extraction efficiency, the SIS300 lattice has been redesigned. With this aim, a code has been developed for optimizing the sextupoles strengths, minimizing the excitation of undesired resonances and correcting the chromaticity to fulfill the Hardt condition. Additionally, the optimization allows the compensation of the b3 field components, steady or time dependent,...

Cyclase-associated protein (CAP) is a highly conserved and widely distributed protein that links the nutritional response signaling to cytoskeleton remodeling. In yeast, CAP is a component of the adenylyl cyclase complex and helps to activate the Ras-mediated catalytic cycle of the cyclase. While the N-terminal domain of CAP (N-CAP) provides a binding site for adenylyl cyclase, the C-terminal d...

81 AP, AS: Institute for Veterinary Pathology, Faculty of Veterinary Medicine, University of Zurich, Switzerland; MK: Animal Health Diagnostic Laboratory and Department of Pathobiology and Veterinary Diagnostic Investigations, Michigan State University, East Lansing, MI 48824. Address correspondence to Dr Matti Kiupel, Department of Pathobiology and Veterinary Diagnostic Investigation, College ...