Nine healthy volunteers were studied on the seventh day of dosing at 21:00 h with nizatidine 150 mg (N 150), nizatidine 300 mg (N 300), ranitidine 300 mg (R 300), or placebo, given in a predetermined random order. The double-blind 24 hour studies, using the Royal Free Hospital standard protocol, simultaneously measured intragastric acidity and plasma gastrin concentration. Compared with placebo...

Hand-held technologies have offered less support for learning about space and measurement than they have for other strands of mathematics. This paper describes a recent development which seems promising in this respect, Casio’s ClassPad 300. The mechanisms of providing interactive opportunities for students are described and illustrated, and some possible ways in which this sort of device might...

The paper presents an automatic method for liver vasculature segmentation in volumetric images obtained during Computed Tomography (CT) patient examination. The method, apart from the CT image, also requires an additional image containing binary liver mask. A modified multiscale vesselness filter (VF) performs vasculature detection. VF response is used to determine the starting voxels for the s...

La Biblioteca Digital de la Universidad de Castilla-La Mancha pretende ser ofrecer todas las posibilidades de una biblioteca tradicional, tanto en cuanto a recursos como a servicios, y no quedarse en una mera colección de textos accesibles pero desorganizados. Se presenta esta biblioteca desde su gestación hasta el momento actual mostrando las posibilidades que ofrece y la experiencia de su pue...

The recent development by Casio of the hand-held ClassPad 300 device raises a number of important questions for the design of mathematical learning experiences for students. This paper provides a brief description of the ClassPad 300 and its mathematical capabilities, followed by a description of the idea of an eActivity, well provided for in the operating system of the device. As their name su...

Insiders trade not only because they have private information about their companies but also because of other exogenous reasons. Therefore, it is important to control for exogenous trading needs in empirical studies regarding insider trading. Lee (1997) shows that insider trading is not closely related to the long-term performance of primary seasoned equity offering firms. This paper examines w...