INTRODUCTION Sunitinib is a multiselective oral inhibitor of several tyrosine-kinase receptors that has demonstrated its efficacy in patients with metastatic and/or unresectable gastrointestinal stroma tumours (GIST) who were resistant to or intolerant to previous treatment with imatinib. The purpose of this study is to assess the cost-effectiveness of sunitinib vs. best supportive care (BSC) i...

In today’s turbulent environment, local self-government administrations are under pressure of various, often conflicting needs, demands and interests that affect their effective operations. Accordingly, an innovative model effectiveness measurement has been applied in this research which effectively includes a broad spectrum organizational goals. Measuring municipal management structures provid...

data envelopment analysis (dea) and balanced scorecard (bsc) are two well-known approaches for measuring performance of decision making units (dmus). bsc is especially applied with quality measures, whereas, when the quantity measures are used to evaluate, dea is more appropriate. in the real-world, dmus usually have complex structures such as network structures. one of the well-known network s...

The traditional four-perspective Balanced Scorecard (BSC) model is suitable for a wide variety of organizations. Other dimensions analysis can be carried out and other perspectives considered in each BSC, depending on the specific characteristics organization or industry. This paper presents evidence that justifies validates inclusion new perspective: ‘environmental sustainability viticulture’i...

This paper analyses the state of implementation of the balanced scorecard (BSC) among Jordanian industrial companies. From an economic perspective, Jordan is an exemplar of an advanced developing nation in the Middle Eastern region. The paper is part of a wider investigation into the usage of Western developed performance measurement diversity techniques in the Jordanian context. A quantitative...

Coastal areas are characterised by the choice of performance measures and/or reference points which may be critical in the environmental management process, determining the success of an Integrated Coastal Zone Management (ICZM) plan. The tools for the strategic control of ICZM plans are particularly important, although they are still not widely used at the local level. The following paper prop...

BACKGROUND Comparative effectiveness and cost-effectiveness data for induction-maintenance (I-M) sequences for the treatment of patients with nonsquamous non-small-cell lung cancer (nsqNSCLC) are limited because of a lack of direct evidence. This analysis aimed to compare the cost-effectiveness of I-M pemetrexed with those of other I-M regimens used for the treatment of patients with advanced n...

As water resources become further stressed due to increasing levels of societal demand, understanding the effect of climate and landuse change on various components of the water cycle is of strategic importance. In this study we used a previously developed hydrologic model of the Black Sea Catchment (BSC) to assess the impact of potential climate and landuse changes on the fresh water availabil...

GSM Network Designs usually offers big challenges for achieving an efficient cost while respecting the complex combinatorial technical constraints. This networks have hundred or thousands BTS. They have their traffic grouped in hubs, then in BSC nodes to reach the MSC. Hubs must be elected within the BTS set and BSC nodes have to be geographically allocated in the available sites. Also, the num...