نتایج جستجو برای: acetaminophen poisoning
تعداد نتایج: 39034 فیلتر نتایج به سال:
Background and purpose: Acetaminophen that is used as an analgesic and antipyretic drug can induce severe hepatotoxicity in humans following accidental or intentional overdose. Taurine is one of the most abundant amino acids in the body that is not incorporated into proteins but is found as a free amino acid in the body. This study aimed at investigating the changes in plasma concentration of t...
Social factors may affect the available sources of toxic substances and causes of poisoning; and these factors may change over time. Additionally, understanding the characteristics of patients with acute toxic poisoning is important for treating such patients. Therefore, this study investigated the characteristics of patients with toxic poisoning. Patients visiting one of 3 hospitals in 2003 an...
Context: Acetylcysteine is an effective treatment for acetaminophen poisoning. The preparation and dose calculation of acetylcysteine associated with medical errors. prevalence this error 34% globally. Case report: A 15-year-old girl took overdose in a suicide attempt. intravenous was ordered. Due to the medication by nurse, she received 10-fold both initial loading maintenance dose, at first d...
STUDY OBJECTIVE Treatment with a shortened duration of oral N-acetylcysteine (20 to 48 hours) after acute acetaminophen poisoning is effective in the prevention of subsequent hepatic failure and death when administered to individuals meeting appropriate laboratory criteria. METHODS Individuals with a potentially toxic acetaminophen ingestion according to serum acetaminophen levels were identi...
Paracetamol (acetaminophen) poisoning. No need to change current guidelines to accident departments.
Paracetamol is an effective, simple analgesic that is well tolerated by adults and children at therapeutic doses. In many countries it is available without prescription. Unfortunately, its ready availability is associated with episodes of poisoning that prompt 3.3% of inquiries to US regional poisons centres, 10% of inquiries to the UK National Poisons Information Service, and up to 43% of all ...
Background: Acetaminophen (APAP), a common analgesic agent, is hepatotoxic in overdose. N-acetylcysteine (NAC), as an APAP antidote, shows anaphylactic reactions and has low efficacy poisoning high doses. Objectives: This study was designed to examine the hepatoprotective effect of biochanin A (BA) mice model acetaminophen-induced hepatotoxicity. Methods: To evaluate APAP-induced oxidative stre...
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