A 58-year-old man presented with complaints of blackish discoloration of forearms and face of five months duration. The lesions occurred episodically after taking anti-cancer medications, each episode lasting for two weeks. Histopathology confirmed a lichenoid eruption. Photolichenoid eruption to docetaxel is a dermatological adverse effect not reported in literature earlier.

introduction: previous studies have raised the probably of cardiac manifestation in tramadol poisoning. however, conclusive information on electrocardiographic (ecg) abnormalities of tramadol overdose remains to be explained. therefore, the present study aimed to evaluate the epidemiology of ecg abnormalities in tramadol poisoned patients. methods: in a prospective cross-sectional study, all pa...

objectives: graft versus host disease (gvhd) is a life threatening reaction in the stem cell transplantation process. nowadays cyclosporine is the most commonly utilized agent for gvhd prophylaxis and it has a major role in successful transplantation. cyclosporine has been applied for many years in this field but it could be stated that currently no general consensus is available for its optima...

objective: to compare the efficacy of intravenous and intraperitoneal injection of lidocaine and normal saline in relieving postoperative pain after elective abdominal hysterectomy. materials and methods: for this double-blind randomized controlled study 109 patients undergoing elective abdominal hysterectomy were randomly allocated to three groups :1) iv group (intravenous injection group) rec...

Ipilimumab is an anti-CTLA-4 antibody that is approved for the treatment of metastatic malignant melanoma. Side-effects are mostly immune-mediated and in many cases the lack of specific symptoms leads to delayed diagnosis and treatment of adverse events. We present the case of a female patient who experienced an uncommon combination of adverse reactions while undergoing therapy with ipilimumab ...

background: myeloablative-allogeneic stem cell transplantation is a common way of treating various malignant and nonma-lignant diseases; but, it is associated with hazardous immediate and late complications. the majority of patients are not good candidates for high dose therapy because of old age, medical co-morbidities or previous heavy treatments. the donor stem cells can engraft in the recip...