Thiabendazole (TBZ), an antifungal and antihelmintic benzimidazole derivative, after 6 min treatment with a 0.1 m M aqueous solution enhances C 0 2 release in intact potato tubers for up to two hours. There are also indications for a reduced water permeability of isolated periderm layers from TBZ treated potato tubers. Potato slices (ca. 3 mm thick) or discs (with ca. 5 mm diameter) from potato...

Momordica charantia L. belongs to the family Curcubitaceae and it is very common in many Brazilian regions. The plant is a liana with flowers and yellow fruits that present red seeds when are ripe. Popularly known as "melão-de-sãocaetano", "melão amargo" or "cabaço-amargo", it possesses many uses: antidiabetic, antihelmintic, antmicrobial, anticancerigenous and antioxidant. The phytochemical pr...

Most Brazilian dairy production is conducted by small holders whose general management skills and feeding programs are often deficient. One common problem directly attributed to underfeeding is that heifers rarely reach sexual maturity before 15 months of age. Groups of growing heifers were treated to detect the effects of protein supplementation and antihelmintic treatment on sexual maturity. ...

Genus Iris is well known rhizomatous herb belonging to family Iridaceae and is represented by 260 species [1]. Iris species have immense medical importance in indigenous systems of medicine and are used in the treatment of liver dysfunction, inflammation, bacterial and viral infections [2,3]. Externally root in powder or poultice is used as an application to sores and pimples [2]. Rhizomes of I...

Emergence of resistance by bacterial and fungal stains towards existing antimicrobial agents is one of the major problem as well as motivation to synthesize a new class of antimicrobial agents possessing potent activity compared to commonly used therapy. Coumarin is the heterocyclic compound formed from benzene and pyrone ring containing oxygen and its derivatives are of wide awareness because ...

  A new bioactive proline-rich cyclohexapeptide - diandrine C (6), previously isolated from whole plant of Drymaria diandra (Caryophyllaceae), was synthesized through coupling reactions of tetrapeptide unit Boc-Gly-l-Pro-l-Tyr-l-Trp-OH with dipeptide unit l-Pro-Gly-OMe using N,N-diisopropylcarbodiimide (DIPC) as the coupling agent, followed by cyclization of l...

Molecular docking is the identification of ligand’s correct binding geometry i.e pose in site and estimation its affinity for rational design drug molecule. The current study endeavored high throughput insilico screening 24 compounds docked with their respective protein using PyRx-Virtual Screening Tool software. Out compounds, almost all test showed a very good score. Fluconazole was used as s...

BACKGROUND Fasciolosis due to Fasciola hepatica is the most important hepatic disease in veterinary medicine. Its relevance is important because of the major economical losses to the cattle industry such as: reduction in milk, meat and wool production; miscarriages, anemia, liver condemnation and occasionally deaths, are estimated in billons of dollars. The emergence of fluke resistance due to ...