BACKGROUND Some clinicians may favor a strategy of early switch to oral antimicrobial therapy for patients responding to initial intravenous therapy. An important relevant consideration refers to the comparative safety and tolerability between oral and intravenous antimicrobial therapy. LITERATURE SEARCH/STUDY SELECTION: We sought to evaluate the above-mentioned issue by performing a systematic...

Infectious diseases form the major health-care burden for the developing world and antimicrobials prove to be the magical drugs to combat this. The discovery of antimicrobial agents was boon for the global health-care system and the wonderful cure by antimicrobials shifted the disease trends from infectious to life-style diseases in the developed world. Sudden appearance of the antimicrobial re...

Antimicrobial combination therapy is a time/resource-intensive procedure commonly employed in the treatment of cystic fibrosis (CF) pulmonary exacerbations caused by Pseudomonas aeruginosa . Ten years ago, most promising antimicrobial combinations were proposed, but there has since been introduction new ?-lactam plus ?-lactamase inhibitor combinations.

Widespread overuse and inappropriate use of antimicrobial drugs continues to fuel an increase in antimicrobial resistance and leads to consequent treatment complications and increased healthcare costs. In the present study we aimed to describe antimicrobial drug consumption and predictors and to identify potential targets for antimicrobial stewardship. This was a prospective observational study...

Antimicrobial agents are commonly used in neonatal foals for the treatment or prevention of sepsis. However, due to concerns about development antimicrobial resistance and increasing pressure on veterinarians rationalise use, we should be trying reduce unnecessary use antimicrobials. This article reviews many important considerations when selecting an foals. Firstly, consider general difference...

introduction: the a im of this study is the evaluation of the effect of antimicrobial photodynamic therapy with radachlorin on staphylococcus aureus and escherichia coli. new windows are open in the antimicrobial field so-call photodynamic therapy that incorporates a nonpoisonous photosensitizer (ps) with innocuous special wavelength photons to excite the ps. methods: two strains of bacteria us...

background & importance: infections of the craniocervical junction are rare. case presentation: we present a case of infection by methicillin-sensitive staphylococcus aureus and streptococcus mitis that was not previously reported. conclusion: neurosurgeons must suspect for diagnosis and initiate broad antimicrobial therapy, including active agents against gram-negative and then initiate a targ...

As leptospirosis is a treatable disease, early diagnosis and prompt treatment are important for better prognosis. Early diagnosis depends on the knowledge of epidemiological factors, presenting features and use of appropriate laboratory tests. Early institution of appropriate antimicrobial therapy in combination with supportive therapy reduces the mortality from this disease. Leptospires are se...