dissection of the sinus of valsalva is a rare and life-threatening event. it often occurs during percutaneous coronary intervention in the right coronary artery (rca). dissection flap usually involves the rca and the right sinus of valsalva. here we report two extremely rare cases of spontaneous dissection limited to the non-coronary sinus of valsalva, causing severe aortic valve regurgitation:...

cardiovascular disorders continue to constitute major causes of morbidity and mortality in diabetic patients. in this study, the effect of chronic administration of sesame (sesamum indicum l) seed feeding was studied on aortic reactivity of streptozotocin (stz)-diabetic rats. male diabetic rats received sesame seed-mixed food at weight ratios of 3% and 6% for 7 weeks, one week after diabetes in...

objective(s): thyroid hormones play an essential role in fetal growth and maternal hypo-thyroidism which leads to cardiovascular deficiency in their offspring.  considering this, we intended to investigate the impact of gestational hypothyroidism on offspring vascular contractibility and possible underlying mechanisms. materials and methods: hypothyroidism was induced in female rats by administ...

a strategy employing moderate hypothermia for the replacement of the aortic arch is proposed to avoid the complications of profound hypothermic circulatory arrest. two patients underwent the complete replacement of the aortic arch using three pumps - for the brain, thoracoabdominal aorta, and heart, respectively. there were no complications and the patients were extubated uneventfully. the meth...

‎this paper presents an application of partial differential equations(pdes) for the segmentation of abdominal and thoracic aortic in cta datasets. an important challenge in reliably detecting aortic is the need to overcome problems associated with intensity inhomogeneities. level sets are part of an important class of methods that utilize partial differential equations (pdes) and have been exte...

objective(s): occludin is essential for proper assembly of tight junctions (tjs) which regulate paracellular endothelial permeability. omega-3 polyunsaturated fatty acids (ω-3 pufa) protect endothelial barrier function against injury. materials and methods: we examined anti-inflammatory effect of ω-3 pufa intake (30 mg/kg/day for 10 days) on expression and location of occludin in the aorta of a...

abstract background and objective: vascular abnormality and dysfunction plays an important role in the pathogenesis of vascular disease in diabetic state. in this study, we aimed to investigate whether an in vitro exposure of endothelium-intact aortic rings to melissa officinalis (lemon balm, mo) aqueous extract could have a beneficial effect in rats with subchronic diabetes. materials and meth...

Introduction: Our previous studies showed that hydroalcoholic extract of leaf of Vitis vinifera relaxes the phenylephrine-induced contraction in rat thoracic aorta. This effect was dependent on endothelial integrity and NO-cGMP system. The vasorelaxant effect of extract was much lesser on KCl-induced contraction. We, therefore, postulated that K+ channels are involved. The main aim of the pr...

Introduction: We did this study because there were a few studies about aorto-branch junction. Methods: Four light microscope and electron microscope study, the abdominal aorta, renal artery, and the adjoining right and left renal arteries were dissected out from 4 neonate dogs. Results: Based on the results, there is only one cell type in the tunica intima of endothelium in both art...