reports have shown the antioxidant, hypotensive, hypolipidemic and vasodilatory effects of grape (vitis vinifera l.) seed extract. we have recently shown the relaxatory effect of grape leaf extract on rat uterus and reduction of frog heart rate and contractility. the aim of the present study was to investigate the relaxant effect of vitis vinifera leaf hydroalcoholic extract (vlhe) on rat thora...

Reports have shown the antioxidant, hypotensive, hypolipidemic and vasodilatory effects of grape (Vitis vinifera L.) seed extract. We have recently shown the relaxatory effect of grape leaf extract on rat uterus and reduction of frog heart rate and contractility. The aim of the present study was to investigate the relaxant effect of Vitis vinifera leaf hydroalcoholic extract (VLHE) on rat thora...

estrogen replacement therapy (ert) in postmenopausal women may decrease the risk of coronary artery diseases (cad). we hypothesized that nitric oxide (no) releasing due to ert may be the essential factor by which endothelial permeability decreases. four groups of ovariectomized rabbits were under investigation for five weeks. groups 1 & 4 received high cholesterol diet and other two groups (2 &...

Reports have shown the antioxidant, hypotensive, hypolipidemic and vasodilatory effects of grape (Vitis vinifera L.) seed extract. We have recently shown the relaxatory effect of grape leaf extract on rat uterus and reduction of frog heart rate and contractility. The aim of the present study was to investigate the relaxant effect of Vitis vinifera leaf hydroalcoholic extract (VLHE) on rat thora...

aortoenteric fistula is a rare but significant clinical entity associated with high morbidity and mortality if remain untreated. clinical presentation and imaging findings may be subtle and prompt diagnosis can be difficult. herein, we present a patient who initially presented with abdominal pain and computed tomography showed an aortic aneurysm compressing duodenum without any air bubbles. one...

objective(s) four novel losartan analogues 5a-d were synthesized by connecting a dihydropyridine nucleus to imidazole ring. the effects of 5a and 5b on angiotensin receptors (at') and l-type calcium channels were investigated on isolated rat aorta. materials and methods aortic rings were pre-contracted with 1 pm angiotensin ii or 80 mm kcl and relaxant effects of losartan, nifedipine, 5a a...

Aortic dissection occurs when a tear develops in the wall of the aorta, which is rare in the young population. This fatal disorder is hard to diagnose, especially in young patients. We present the case of aortic dissection in a 15-year-old boy referred to the Emergency Department of Yazd University of Medical Sciences in November 2015. The patient presented to our department with sudden acute c...

aorta is formed in a dynamic environment which gives rise to imbalances between many forces that tend to extend the diameter and length. furthermore, internal forces tend to resist this extension. impedance tomography can show this imbalance to stimulate the stenosis of aortic valve, growth of the elastic, collagen and to effectively reduce the stresses in the underlying tissue. in blood flow, ...

mycotic pseudoaneurysm of the ascending aorta is rare in patients undergoing coronary artery bypass graft (cabg) and usually caused by staphylococcus aureus. we describe a patient with a mycotic pseudoaneurysm of the ascending aorta at the proximal vein graft anastomosis site after cabg. culture from the sinus tract of the sternum and from the aneurysm sac was klebsiella pneumoniae. surgical te...

we report a unique case of chronic dissection of the ascending aorta complicated with huge and thrombotic pseudoaneurysm in a patient with coarctation of descending aorta. preoperative investigations such as transesophageal echocardiography (tee) confirmed the diagnosis of dissection. intraoperative findings included a12 cm eccentric bulge of the right lateral side of dilated the ascending aort...