introduction: serum lipid disorders are one of the important risk factors for development of coronary arterial atherosclerosis. the aim of this study was to compare the effects of the drug lovastatin and a liquid vegetable extract (dill) on blood plasma lipid levels of rats. methods: in this experimental study, 32 mouse vistar rats weighing 250±30 grams were included and maintained at 23±1 degr...

objective(s) homocysteine, hs-crp and fibrinogen are three novel cardiovascular risk factors. the aim of this study was to examine the effect of a single bout of circuit resistance exercise on homocysteine, hs-crp and fibrinogen levels in healthy and inactive men. materials and methods the subjects were randomly divided into the experimental group (n= 14) and the control group (n= 9). circuit t...

Recent studies in single cell RNA sequencing have improved understanding of the structure immune subpopulation atherosclerosis. With help novel technologies, new subpopulations cells involved atherosclerosis been identified. In addition, a following relatively common and strong cardiovascular risk factor has emerged: clonal hematopoiesis indeterminate potential resulting from accumulation somat...

visit-to-visit variability (vvv) in blood pressure (bp) creates challenges to hypertension control and was independent associated with increased all-cause mortality in hypertensive patients. the major goal of the present study was to investigate the association of vvv in systolic (s)bp with progression of carotid atherosclerosis and en-dothelial dysfunction in on-treated hypertensive patients.o...

background: atherosclerosis, a chronic inflammatory disease of the vessel wall is characterized by local and systemic immune responses to a variety of antigens. oxidized low-density lipoprotein (oxldl) is considered as an important determining factor in the pathogenesis of atherosclerosis. objective: the purpose of this study was to investigate the degree of peripheral blood mononuclear cells (...

although genetic variants that affect susceptibility to coronary artery disease (cad) have been greatly known, a number of these single nucleotide polymorphisms (snps) remain to be analyzed in populations with different ethnicities. cad is influenced by numerous genetic, environmental, and lifestyle factors, and is an important reason for mortality around the globe. in this study, a novel snp (...

Introduction: Obese individuals have elevated levels of inflammatory and cell adhesion molecules that can critically induce the occurrence of atherosclerosis. Aerobic exercise training reduces biochemical markers and anthropometric characteristics involved in atherosclerosis. However, little is known about the effect of resistance exercise training on these biomarkers. This study aimed to inves...

Atherosclerosis is an independent risk factor for cardiovascular diseases, which related to dyslipidemia, endothelial injury, inflammation, thrombosis, dysfunction of vascular smooth muscle cells and macrophages, etc. Puerarin, a natural monomer from Chinese herb Pueraria lobata, presents multiple protective activities. The paper firstly reviewed the factors drug atherosclerosis. And then, extr...

background: a precise understanding of the mechanism of human neointimal stenoses and atherosclerotic fibrous plaques , which give rise to thromboses in vital arteries, requires a suitable animal model that would mimic the same characteristics well. we developed a rabbit model of neointimal stenosis and fibrotic plaque rupture in the carotid artery to visualize the lesion progress and to charac...