Thyroid cancer is the second most common cancer diagnosed during pregnancy after breast cancer. The goal of management is to control malignancy and prevent maternal and fetal complications as a result of maternal hypothyroidism. The role of female sex hormones as an etiologic factor was investigated, with no clear association. Pregnancy can cause an increase in size of a previously existed thyr...

estational trophoblastic disease includes following forms of growth disturbance of the human trophoblast: hydatiform mole, invasive mole, choriocarcinoma and placental site trophoblastic tumors. Term gestational trophoblastic disease is applied to the letter three conditions. Diagnosis and decision to institute treatment are sometimes undertaken without histopathological finding. Gestational tr...

Although Graves’ disease continues to be considered the most frequent cause of clinical hyperthyroidism in pregnancy, disproportionately high production human chorionic gonadotropin (HCG) as occurs gestational trophoblastic (TSG), is another possible that should when evaluating thyrotoxicosis pregnancy. A 19-year-old female with unremarkable past medical history who was admitted for nausea, vom...

AIM To rule out maternal and pregnancy factors that may contribute to platelet count (PLT) changes in the first trimester of gestation and examine if there is any association between its levels and adverse perinatal outcome. METHODS The study population included all patients from the first-trimester visit between 2013-2015 with pregnancy results. Linear multiple regression was constructed to ...

OBJECTIVE To describe a novel technique for localizing small testicular mass during testicular-sparing surgery (TSS). METHODS AND RESULTS A 20-year-old man presented with bilateral testicular masses. Both alpha-fetoprotein (AFP) and beta-human chorionic gonadotropin (BHCG) levels were raised. Clinical and imaging studies revealed a 2.7 cm and 0.7 cm mass in the right and left testis, respecti...

T he discovery of fetal DNA in the plasma of pregnant women has led to the development of promising approaches for non-invasive prenatal diagnosis. However, as fetal and maternal DNA species co-exist in maternal plasma, these DNA based diagnostic applications depend largely on the use of genetic markers that would allow the discrimination between fetal and maternal DNA (for example, the Y chrom...

Gestational trophoblastic disease (GTD) is a group of several rare tumours that arise in the uterus from placental cells during pregnancy. These are benign majority cases but may be malignant. A 38-year-old woman, Gravida 4 Para 1 A3, was admitted at term 19 weeks amenorrhea +6Days for Fetal death utero (FDIU). evacuation induced medically by misoprostol. The ultrasound showed persistent thicke...