By establishing sensitive nested reverse transcription-PCRs for the detection of mRNA of a-fetoprotein (AFP) and b human chorionic gonadotropin (bhCG), we investigated the presence of circulating tumor cells in the peripheral blood of 119 patients with germ-cell tumor. A total of 336 blood samples obtained before and during therapy were examined with regard to clinical applicability. The overal...

Bilateral spontaneous tubal ectopic pregnancy is the rarest form of extra uterine pregnancy. The diagnosis is usually made intraoperatively and levels of serum BHCG and ultrasound has not been useful in the diagnosis of bilateral tubal ectopic pregnancy. A 33-year-old woman with 8 weeks amenorrhea and sever lower abdominal pain was admitted. A transvaginal pelvic ultrasound revealed left adnexa...

Ovarian ectopic pregnancies are a rare occurrence; however the incidence is on the rise. Preoperative diagnosis remains difficult due to nonspecific clinical symptoms and USS findings. Most patients undergo diagnostic laparoscopy with subsequent surgical management. We present the case of a 32-year-old female who presented with vaginal bleeding and an unsited pregnancy, with a BhCG of 24693. Fo...

Gestational trophoblastic disease (MTG) groups together conditions that are very variable from a clinical, biological and metastatic potential point of view.We report case ruptured molar pregnancy, diagnosed by picture hemorrhagic shock, confirmed histological examination the surgical specimen. Monitoring was assaying plasma BhCG levels.

Invasive mole also known as chorioadenoma destruens comprises about 15 % of all gestational trophoblastic neoplasia [1]. It is a trophoblastic tumor characterized by myometrial invasion by direct extension or through venous channels. The most common presenting symptom is vaginal bleeding (97 %) [2]. The diagnosis is usually suggested after a hydatidiform mole is removed and bhCG remains elevate...

Gestational trophoblastic tumor (GTT) most commonly follows a molar pregnancy. In fact, it can occur following gestational events such as induced or spontaneous abortion, ectopic pregnancy, and term pregnancy. In this study, we present the case of a patient with ectopic pregnancy who was treated with a single dose of methotrexate (MTX). The maximum titer of beta subunit of human chorionic gonad...

Key Clinical Message Choriocarcinoma of the fallopian tube is extremely rare and highly susceptible to early metastasis. manifestations ectopic pregnancy choriocarcinoma are same, all patients with should be evaluated for based on histopathological findings. Adjuvant chemotherapy (after surgery) proposed treatment tubal choriocarcinoma. Abstract a malignant epithelial tumor chorionic villi that...