The purpose of this study was to investigate the effects of Bioglass 45S5 and Biosilicate, on bone defects inflicted on the tibia of rats. Fifty male Wistar rats were used in this study, and divided into five groups, including a control group, to test Biosilicate and Bioglass materials of two different particle sizes (180-212 microm or 300-355 microm). All animals were sacrificed 15 days after ...

OBJECTIVES We describe the histopathology of ossicular grafts and implants so as to provide insight into factors that may influence functional results after surgery for chronic otitis media. METHODS Histopathologic observations were made on 56 cases: 50 surgical specimens and 6 temporal bone cases in which the graft was sectioned in situ. RESULTS AND CONCLUSIONS Autogenous malleus, incus, a...

Highly porous composites scaffolds of poly-D,L-lactide (PDLLA) and poly(lactide-co-glycolide) (PLGA) containing different amounts (10, 25 and 50wt%) of bioactive glass (45S5 bioglass) were prepared by thermally induced solid-liquid phase separation (TIPS) and subsequent solvent sublimation. The addition of increasing amounts of bioglass into the polymer foams decreased the pore volume. Converse...

Abstract In this study, the bioactivity and mechanical properties (Mechanical compressive strength, Hardness, density) of bioglass (BG) bioglass/graphene oxide (BG/GO) were investigated. Bioglass in chemical composition [60SiO2_35CaO_5P2O5] was prepared via sol–gel method. GO added to with different contents (0.5, 1, 2, 3) wt.% named as 0.5%GO, 1%GO, 2%GO, 3%GO samples respectively. The synthes...

This research has been done to study characteristic and biocompatible evaluation of a nano-biocompositeceramic with the bioglass (BG) as a first phase. In this regard, synthesis of S53P4 (53% SiO2, 4% P2O5,23% Na2O and 20% CaO) bioglass has been considered as the first phase and flourapatite (FA) consideredas the second phase. Afterwards, nanocomposite with the base of S53P4 b...

Fabrication of mechanically competent bioactive scaffolds is a great challenge in bone tissue engineering. In this paper, β-tricalcium phosphate (β-TCP) scaffolds were successfully fabricated by selective laser sintering combined with furnace sintering. Bioglass 45S5 was introduced in the process as liquid phase in order to improve the mechanical and biological properties. The results showed th...

This study investigated, both histologically and histometrically, the efficacy of enamel matrix derived proteins (EMD) associated with bioactive glass (BG) and an absorbable membrane in the treatment of class III furcation defects in mongrel dogs. After surgical defect creation and chronification, the lesions were randomly divided into three groups according to the treatment employed: Test Grou...

Fabrication of 3-D highly porous, bioactive, and mechanically competent scaffolds represents a significant challenge of bone tissue engineering. In this work, Bioglass®-derived glass-ceramic scaffolds actually fulfilling this complex set of requirements were successfully produced through the sponge replication method. Scaffold processing parameters and sintering treatment were carefully designe...