DP-bioglass paste has been demonstrated to produce 60 microm of sealing depth on exposed dentinal tubules. However, the occlusive effect depended on a continuous placement of DP-bioglass paste on dentinal surface for three days. In a bid to fabricate highly reactive DP-bioglass particles, a sol-gel method was used together with HNO3, NaOH, and H3PO4 as catalysts. As a result, the application ti...

CONTEXT Many synthetic bone materials have been introduced for repairing bone defects. AIM The aim of this study is to comparatively evaluate the efficacy of nano-hydroxyapatite (HA) and nano-bioglass bone materials with their traditional micro counterparts in repairing bone defects. MATERIALS AND METHODS In this prospective animal study, four healthy dogs were included. First to fourth pre...

Particulate 45S5 Bioglass with an average size of 46 microm was incorporated into a high density polyethylene (HDPE) for potential medical applications. Composites with Bioglass volumes of 10, 20, and 40% were produced by a manufacturing process consisting of blending, compounding, powdering, and compression molding. The Bioglass particles were well dispersed, and their homogeneous distribution...

The interfacial characteristics between bioactive glass (45S5 Bioglass) surfaces and poly(α-hydroxyacid) melts have been assessed by direct wetting measurements. In particular, the wettability of Bioglass powder by poly(D,Llactide) (PDLLA) and poly(D,L-lactide-co-glycolide) (PLGA) was assessed by imbibition measurements. Additionally, the equilibrium contact angles of PDLLA and PLGA melts on a ...

Calcium sulfate (CaSO₄), as a promising tissue repair material, has been applied widely due to its outstanding bioabsorbability and osteoconduction. However, fast disintegration, insufficient mechanical strength and poor bioactivity have limited its further application. In the study, CaSO₄ scaffolds fabricated by using selective laser sintering were improved by adding 45S5 bioglass. The 45S5 bi...

Bioactive and bioresorbable composite materials were fabricated using macroporous poly(DL-lactide) (PDLLA) foams coated with and impregnated by bioactive glass (Bioglass) particles. Stable and homogeneous Bioglass coatings on the surface of PDLLA foams as well as infiltration of Bioglass particles throughout the porous network were achieved using a slurry-dipping technique in conjunction with p...

Titanium β-type alloys attract attention as biomaterials for dental applications. The aim of this work was the synthesis of nanostructured β type Ti23Mo-x wt % 45S5 Bioglass (x = 0, 3 and 10) composites by mechanical alloying and powder metallurgy methods and their characterization. The crystallization of the amorphous material upon annealing led to the formation of a nanostructured β type Ti23...

Bone can be affected by osteosarcomae requiring surgical excision of the tumor as part of the treatment regime. Complete removal of cancerous cells is difficult and conventionally requires the removal of a margin of safety around the tumor to offer improved patient prognosis. This work considers a novel series of composite scaffolds based on poly(octanediol citrate) (POC) impregnated with galli...

This study investigated the possibility of incorporating alpha-tocopherol (vitamin E) into poly(3hydroxybutyrate) (P(3HB))/Bioglass composites, which are being developed for bone tissue engineering matrices. P(3HB) films with 20 wt% Bioglass and 10 wt% vitamin E were prepared using the solvent casting technique. Addition of vitamin E significantly improved the hydrophilicity of the composites a...

Bioglass® 45S5 is widely used in biomedical applications due to its ability to bond to bone and even to soft tissues. The sintering ability of Bioglass powders is a key factor from a technological point of view, since its govern the production of advanced devices, ranging from highly porous scaffolds to functionalized coatings. Unfortunately this particular glass composition is prone to crystal...