We describe a case where bispectral index (BIS) monitoring was used successfully to guide an inhaled induction technique for a difficult airway. The patient was a 34 years old male who had a previous history of awareness during anaesthesia. He was also morbidly obese with a Mallampatti score of III on preoperative examination.

A comatose patient required a tracheostomy. His Glasgow Coma Score was 4 and he was intubated with mydriatic and isochoric pupils, without corneal and light reflexes. Two previous EEGs showed signs of severe and diffuse encephalopathy (arreactive delta and theta rhythms) and there were no somatosensory evoked potentials recordable at the scalp. When the tracheostomy procedure was carried out, t...

Bispectral index (BIS) monitoring is commonly used to provide a measure of depth during general anaesthesia in attempt to reduce the rare occurrence of awareness [1,2]. The Bispectral Index is a generated number between 0 and 100 that is derived through utilization of a number of advanced EEG signal processing techniques including bispectral analysis, power spectral analysis, and time domain an...

The primary aim of this study was to test whether dexmedetomidine administration based on the bispectral index (BIS) monitoring caused a reduction in consumption of sevoflurane. Following Institutional Ethic Committee approval and written informed consent from all parents, fifty-four children undergoing sevoflurane anaesthesia randomly allocated to receive either dexmedetomidine (Group D) or sa...

BACKGROUND Bispectral Index (BIS) has been used to measure sedation depth. Ideally, to guide anesthetic management, range of BIS scores at different sedation levels should not overlap, and BIS should be independent of drug used. This study assessed ability of BIS to predict sedation depth between sevoflurane, propofol, and midazolam. Quality of recovery was also compared. METHODS Patients und...

To the Editor: We read with great interest the results of the largest Bispectral Index (BIS) monitoring study ever performed, which was published in the October 2012 issue of Anesthesiology.1 No significant difference in intraoperative awareness with explicit recall was detected between BIS and anesthetic concentration protocols (0.08 vs. 0.12%, P = 0.48) in an unselected surgical population of...

BACKGROUND Flumazenil is an imidazobenzodiazepine that promptly reverses via competitive inhibition the hypnotic/sedative effects of benzodiazepines on gamma-aminobutyric acid receptors. Endogenous benzodiazepine ligands (endozepines) were isolated in urine, cerebrospinal fluid, and breast milk of women who had not received benzodiazepines. The bispectral index (BIS), an electroencephalographic...

INTRODUCTION To obtain the optimal anesthesia depth is not easy in cardiovascular surgery patients where the haemodynamic reserve is limited, due to reasons such as not being able to give the desired dose of anesthetic agent, or the change in the pharmacokinetics of the agent in the heart-lung machine. This study was planned to assess the contribution of bispectral index (BIS) monitoring in the...

This pilot study looks at the clinical application of bispectral index (BIS) monitoring within the palliative care situation. Using this instrument, the level of awareness in 12 patients was tracked from the onset of unconsciousness until death, and the levels were then related to the patients' clinical state and treatment. The results give a surprising insight into the nature of unconsciousnes...

BACKGROUND The accuracy of the bispectral index (BIS) as a monitor of consciousness has not been well studied in patients who have abnormal electroencephalograms (EEG). METHODS We studied the changes in BIS, its subparameters, and spectral entropy of the EEG during 18 electroconvulsive treatments under propofol and succinylcholine anaesthesia. A single bifrontal EEG, and second subocular chan...