abstract introduction: there is limited knowledge available on the metabolism of glucose in the brain, an insulin insensitive organ. insulin receptors hybridize with insulin like growth factor receptor (igf-i) to transduce the signals in different areas of the brain. in this article we aimed at investigating whether the expression of igf-i receptor and igf-i binding proteins (igfbp1) is changed...

leukodystrophies are metabolic disorders of the brain, spinal cord and, in part, of the peripheral nerves that lead to degeneration of the white matter (myelin) of the brain. since mainly nerve tracts, which control voluntary movement, are embedded in myelin, patients with leukodystrophy suffer from progressive movement disorders and later also from mental deterioration. through a survey, we ca...

A 61-year-old man developed progressive gait imbalance and papular skin lesions over 9 months. He reported fatigue, but no other constitutional symptoms. Neurologic examination revealed ataxia. Brain MRI (figure 1, A–D) demonstrated punctate enhancing foci supratentorially patchy pontine T2 hyperintensity; pituitary or orbital abnormality was reported. Skin biopsy 2) a histiocytic neoplasm that...

Abstract Background Tubercular infection of the brain and spine is relatively common in endemic regions world. Central nervous system tuberculosis can have varied manifestations. The familiar imaging findings are hydrocephalus, ring-enhancing tuberculomas, meningeal enhancement, having a preference for basal regions. Myelitis most manifestation spine, with holocord involvement being rare presen...

despite progress in pharmacological and surgical treatments of epilepsy, little is known about the processes that a healthy brain is rendered epileptic after seizure occurrence. growing evidence supports the involvement of inflammatory processes, both the adaptive immunity and systemic inflammatory response, in induction of individual seizures as well as in the epileptogenesis. clinical and exp...

Despite progress in pharmacological and surgical treatments of epilepsy, little is known about the processes that a healthy brain is rendered epileptic after seizure occurrence. Growing evidence supports the involvement of inflammatory processes, both the adaptive immunity and systemic inflammatory response, in induction of individual seizures as well as in the epileptogenesis. Clinical and exp...

background: hydatidosis is one of the major zoonotic diseases that cause considerable public health problems in iran. the present study was designed to investigate pediatric hydatidosis in pa­tients referred to the children medical center hospital in tehran, iran during 2005-2010. methods : data were collected from the records of 17 patients referred to the center with hydatidosis. data include...