PURPOSE The human cornea, a tissue much exposed to oxidative stress, is rich in extracellular superoxide dismutase (SOD). In this study, the contents and distributions of the SOD isoenzymes in the normal human cornea were compared with those in corneas affected by keratoconus and bullous keratopathy. METHODS The central and peripheral parts of normal human corneas were analyzed separately. Ce...

purpose: to compare clinical and confocal scan outcomes after descemet stripping automated endothelial keratoplasty (dsaek) performed for fuchs’ endothelial dystrophy versus pseudophakic bullous keratopathy. methods: in this retrospective comparative study, 47 consecutive eyes of 39 patients with the diagnosis of fuchs’ endothelial dystrophy (n=29, group 1) or pseudophakic bullous keratopathy (...

purpose: to evaluate the visual outcomes and complications of deep lamellar endothelial keratoplasty (dlek) for management of corneal endothelial disorders. methods: from 2003 to 2005, nine eyes of nine patients with severe bullous keratopathy due to endothelial dysfunction underwent dlek. uncorrected (ucva) and best-corrected (bcva) visual acuity were evaluated pre- and one week, 1, 3 and 6 mo...

OBJECTIVE To evaluate long-term anatomical and functional outcomes of a modified osteo-odonto-keratoprosthesis (OOKP) technique for treatment of corneal blindness from various etiologies. METHODS Two-hundred three patients (224 eyes) underwent modified OOKP surgery between 1973 and 1999. Of the original cohort, 181 patients (98 men and 83 women; mean [SD], age 54.3 [15] years) in whom a stand...

PURPOSE To report the outcome of Descemet stripping automated endothelial keratoplasty (DSAEK) for bullous keratopathy after Sato anterior-posterior radial keratotomy (APRK). METHODS The clinical records of patients who had DSAEK surgery for bullous keratopathy after APRK were reviewed. RESULTS Five eyes of 4 patients (4 men) were included. The mean age at DSAEK surgery was 81.8 ± 7.1 years...

Subepithelial fibrosis (SEF) and the transdifferentiation of keratocytes into fibroblasts or myofibroblasts (Fbs/MFbs) have been detected in the cornea of individuals with bullous keratopathy. We examined the anterior cornea of bullous keratopathy patients for such changes after Descemet's stripping automated endothelial keratoplasty (DSAEK). Twenty-two individuals who underwent unilateral DSAE...

To relate a case not described previously in the national multilateral ophthalmological literature of Descemet’s membrane. A 59-year-old pseudophakic woman diagnosed with bullous keratopathy underwent penetrating keratoplasty an unusual finding multiple layers membrane, which were variable shape and thickness. In addition, ovoid bodies negative Gocott-Gomori (GMS) color present. Discussion Conc...

PURPOSE To establish the effectiveness of amniotic membrane transplantation (AMT) in relieving pain and discomfort in patients with painful bullous keratopathy and its role in improving vision in eyes with visual potential. METHODS Seven eyes of seven consecutive patients with painful corneal conditions were included in a retrospective interventional noncomparative case series performed at Ma...