Introduction Cancers are among the worst noncommunicable diseases around the world. Head and neck cancers are ranked as the fifth most common cancers worldwide. As there are different distributions of risk factors around the world, the incidence of these cancers varies from one place to another. Materials and Methods: We conducted a descriptive analytic cross-sectional study, based on census-ba...

Background and aim: Skin cancer is the most common human cancer. Ultraviolet radiation is now recognized as the most important risk factor for skin cancer development. Light skin colored individuals that spend more time outdoors in day are more susceptible to disease. In this study skin cancer situation in Yazd (located in a hot, dry and desert area) was reviewed.Materi...

EDITORIAL article Front. Oncol., 10 July 2023Sec. Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers Volume 13 - 2023 | https://doi.org/10.3389/fonc.2023.1248807

PARP inhibition with olaparib is a treatment high efficacy in HR deficient cancers that arise carriers of germline mutation the BRCA1/2 genes, particularly ovarian cancer, registered indication. Olaparib also active other related cancers, including breast, prostate and pancreatic cancer. acts through synthetic lethality cancers. responses have however been documented which no mutations were fou...

Exposure to stray neutrons increases the risk of second cancer development after proton therapy. Previously reported analytical models of this exposure were difficult to configure and had not been investigated below 100 MeV proton energy. The purposes of this study were to test an analytical model of neutron equivalent dose per therapeutic absorbed dose  at 75 MeV and to improve the model by re...

BACKGROUND Due to improvements in early detection, supportive care, and treatment, the number of cancer survivors in the United States has tripled since 1971 and is growing by 2% each year. In 2001, there were approximately 10 million cancer survivors, representing 3.5% of the population. As survival after a diagnosis of cancer improves, quantification of the late effects of cancer and its ther...

The risk of second cancers in Merkel cell carcinoma (MCC) remains uncertain since risk estimates vary worldwide. The global MCC population is growing and there is a demand for better knowledge of prognosis of this disease. The Cochrane Database of Systematic Reviews, MEDLINE, and EMBASE search engines were searched for the relevant literature between January 1999 and September 2014 by use of ex...