نتایج جستجو برای: cd4 cd8 ratio
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In adult life, the high CD4:CD8 cell ratio observed in peripheral lymphoid organs originates in the thymus. Our results show that the low peripheral CD4:CD8 cell ratio seen during fetal life also has an intrathymic origin. This distinct production of CD4(+)CD8(-) and CD4(-)CD8(+) thymocytes is regulated by the developmental age of the thymic stroma. The differential expression of Notch receptor...
in order to study and evaluate the indirect immunofluorescent test and the ratio of cd41ymphocytes to cd8 lymphocytes, 97 cases of positive candida cultures were selected from among 400 patients referring to the hospital and suspected of candidiasis. in this study 39% of the patients had an antibody titer less than 1: 160 no significant correlation was seen between canclidiasis and the results ...
Background: The purpose of this study was to evaluate “the effect of intensive activity and regular exercise with carbohydrate ingestion on cortizol, lymphocyte, monocyte, white blood cell, fast blood suger, CD3, CD4, CD8 and CD4 to CD8 ratio, cell-mediated immunity”. Methods: This semi experimental, cross sectional and double blind study performed to investigate the responses of cell-...
چکیده: بیماری سل بوسیله مایکوباکتریومهای بیماریزا از جمله mycobacterium tuberculosis ایجاد می گردد. طبق گزارش who، بیش از یک سوم جمعیت جهان آلوده به این باکتری هستند که بیش از 90 درصد آنها بدون علامت می باشند. این افراد تحت عنوان latent tuberculosis یا افراد ltbi معرفی می گردند. در این پژوهش، سیستم ایمنی اکتسابی در افراد مبتلا به سل فعال و سل نهفته، مورد مقایسه و آنالیز قرار گرفت. پروفایل سای...
BACKGROUND For resource-poor countries, affordable methods are required for enumeration of CD4(+) T lymphocytes of HIV-positive patients. For infants, additional determination of CD4/CD8 ratio is needed. METHODS We determine the CD4(+) and CD8(+) T lymphocytes as the CD3(+)CD4(+) and CD3(+)CD8(+) population of blood cells. Target cells are CD3-immunomagnetically separated from the whole blood...
BACKGROUND A low CD4/CD8 ratio has been identified in the general population as a hallmark of inmmunosenescence and a surrogate of all-cause mortality. We aimed to investigate in treated HIV-infected individuals the relationship between the CD4/CD8 ratio and serious non-AIDS events. METHODS Case-control study within a prospective hospital-based cohort of HIV-infected subjects during at least ...
AbstractBackgroundcontributes substantially to patient morbidity and mortality.In this study we investigatedthe range and distribution of T-lymphocyte. Subsets CD3helper/inducer cell,.th ), CD8: Severe immunosuppression occurs after large thermal burn and probably+ (T cells) CD4+ (T+ (T suppressor /Cytotoxic cells ,TS/C), CD3+CD4thermal injury.+/CD3+CD8+ ratio, CD19+ (B cells) and CD16+ (NK cel...
مقدمه: لوسمی لنفوبلاستی حاد سلولt (t-all) حاصل نقص در بلوغ پیشتاز سلول t به سلول t بالغ می باشد. t-all یکی از انواع بدخیمی های خونی است که پیش آگهی ضعیفی دارد. به منظور دستیابی به یک روش درمانی موفق، درک و شناخت بیولوژی تکامل سلول t و مولکول هایی که در این فرایند تکاملی شرکت دارند ضروری می باشد. در این مطالعه، از رده سلولی jurkat t، که برای بررسی آزمایشگاهی t-all به عنوان سلول های مدل اثبات شده...
The current guidelines for the use of antiretroviral therapy in Nigeria places emphasis on the use of CD4+ enumeration to take decision of initiating antiretroviral therapy and HIV disease monitoring. CD4+ counts are known to be inherently inconsistent and therefore could be misleading. This study was undertaken to analyze the CD4+/CD8+ ratio vis-à-vis CD4+ in HIV-1 infected individual in North...
mitochondrial functions have a major impact on t-cell functionality. in this study we characterized whether mitochondrial function in the neonatal t-cells differs from that in the adult t-cells during short t-cell activation. methods: we used fow cytometry methods to test mitochondrial mass and to monitor mitochondrial ca2+ levels, mitochondrial potential and superoxide generation in parallel w...
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