نتایج جستجو برای: cervical cancer tissue
تعداد نتایج: 1780014 فیلتر نتایج به سال:
background: this study aimed to explore the experiences of iranian women regarding the barriers to and facilitating factors for cervical cancer screening. methods: eight focus groups (n= 86 participants) were conducted with women referred to a health center in karaj, iran from january to march, 2007. purposeful sampling was used. married women aged 18 years old and over, not suffering from obst...
background: by presenting this case we aimed to describe an uncommon complication of generalized peritonitis following spontaneous pyometra perforation in untreated cervical carcinoma. case presentation: this report describes a 60-year-old postmenopausal woman presenting with clinical features mimicking intestinal perforation who was later diagnosed as cervical carcinoma with pyometra perforati...
objective(s): although several chemical and physical methods for gene delivery have been introduced, their cytotoxicity, non-specific immune responses and the lack of biodegradability remain the main issues. in this study, hydroxyapatite nanoparticles (nps) and 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (dope)-modified hydroxyapatite nps was coated with antisense oligonucleotide of e6 mrna...
To analyze Survivin, MMP-2, and MMP-9 expression in different types of cervical lesions and discuss their correlation and clinical significance. Patients with chronic cervicitis, cervical intraepithelial neoplasia, or cervical cancer in our hospital were collected. ELISA was applied to detect the level of Survivin, MMP-2 and MMP-9 in serum. Immunohistochemistry was used to measure Survivin, MMP...
Background and purpose: Cervical cancer is the third leading cause of cancer-related death in women. There are not enough information about the trends of this cancer in Iran, so, this study aimed to investigate the incidence and trends of changes in incidence of cervical cancer in Iran. Materials and methods: This study was a reanalysis of existing data (2003-2009) obtained from the National C...
We previously mapped a nonrandom frequent loss of heterozygosity (LOH) region in cervical cancers to 1 Mb of 6p23. Here, we describe the identification of a novel cervical cancer susceptibility gene, CD83. The gene was identified by several complementary approaches, including a family-based association study, comparison of transcript expression in normal and cancerous tissue, and genomic sequen...
Membrane type 1 matrix metalloproteinase (MT1-MMP) is frequently expressed by cancer cells and is believed to play an important role in cancer cell invasion and metastasis. However, little is known about the role of MT1-MMP in mediating invasiveness of cervical cancer cells. In this study, we examined MT1-MMP expression in 58 primary human cervical tissue specimens, including normal cervix, low...
Cervical cancer is an infectious cancer and the most common gynecologic cancer worldwide. E6/E7, the early genes of the high-risk mucosal human papillomavirus type, play key roles in the carcinogenic process of cervical cancer. However, little was known about its roles in modulating tumor microenvironment, particular extracellular matrix (ECM). In this study, we found that E6/E7 could regulate ...
Cervical cancer, a malignant disease that invades the uterine cervix, is preceded by a long phase of precursor lesion known as cervical intraepithelial neoplasia. (CIN). The present study investigated the clinical utility of total sialic acid and lipid-bound sialic acid (LSA) levels in CIN and cervical cancer. The present study also investigated histochemical expression of glycoproteins in cerv...
BACKGROUND Although the incidence of cervical cancer has reduced during last years, but it causes mortality among women. Many efforts have performed to develop new drugs and strategy for treatment of cervical cancer. Adipose Tissue-Derived mouse Mesenchymal Stem Cells (MSCs) has many advantages which make them a suitable choice as a cell therapeutic agent in cancer treatment. In this study, we ...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید