Thermoplastic polyurethane (TPU)/clay nanocomposites were prepared via a melt-compounding method using ester type TPU and two different modified organoclays (Cloisite 30B and Cloisite 15A) in different contents. The Effects of the chemical structure and content of the nanoclays on the thermal degradation and mechanical properties of TPU were also investigated. The effect of structural modificat...

     The aim of this study is to prepare novel sorbitol based extended release tablets by melt dispersion method using carbamazepine as a model drug. Carbamazepine was melted along with sugar alcohol to get melt dispersion granules (MGDs) and was characterized by differential scanning calorimetry (DSC), powder X-ray diffractometry (XRD) and solubility study. The physical and chemical parameters...

The measure of delayed ventricular repolarization most frequently used clinically is the ability of the new chemical entity to prolong the QTc interval on surface electrocardiogram. Intramyocardial dispersion of repolarization appears to play a more important role both in electrical stability of the ventricles and in arrhythmogenesis. The potential importance of myocardial dispersion of refract...

This paper describes the biological motivation, design and testing of a novel obstacle sensor system based on the chemical sounding mechanism observed in slime molds. The sensor system emits a volatile sounding chemical and adjacent obstacles reduce the dispersion of the chemical. The resulting increase in chemical concentration is detected and interpreted as indicating an obstacle. To demonstr...

in this study, the morphological and chemical properties of carob pods and carob beans as well as the effect of different extraction, and purification methods on the physical and chemical properties of the purified gums have been investigated. in order to dehusk carob beans, boiling water as well as acidic methods were used. the endosperm powder was prepared and the effect of endosperm powder c...

Accurate modeling of the molecular environment is critical in condensed phase simulations of chemical reactions. Conventional quantum mechanical/molecular mechanical (QM/MM) simulations traditionally model non-electrostatic non-bonded interactions through an empirical Lennard-Jones (LJ) potential which, in violation of intuitive chemical principles, is bereft of any explicit coupling to an atom...

Detailed understanding of protein function and malfunction hinges on the ability to characterize transiently populated states and the transitions between them. Here, we use (15)N, , and (13)CO NMR R(2) relaxation dispersion to investigate spontaneous unfolding and refolding events of native apomyoglobin. Above pH 5.0, dispersion is dominated by processes involving fluctuations of the F-helix re...

Pore structure and connectivity determine how microstructured materials perform in applications such as catalysis, fluid storage and transport, filtering or as reactors. We report a model study on silica aerogel using a time-of-flight magnetic resonance imaging technique to characterize the flow field and explain the effects of heterogeneities in the pore structure on gas flow and dispersion wi...

The interaction of chemical dispersants and suspended sediments with crude oil influences the fate and transport of oil spills in coastal waters. A wave tank study was conducted to investigate the effects of chemical dispersants and mineral fines on the dispersion of oil and the formation of oil-mineral-aggregates (OMAs) in natural seawater. Results of ultraviolet spectrofluorometry and gas chr...