The choice of drug therapy in pregnant patients suffering from vaginal infections is limited by the safety profile of the drug. Assuring the efficient topical therapy to avoid systemic absorption is considered the best therapy option. Chitosan-coated liposomes have been developed and optimized to assure localized therapy of clotrimazole. Chitosan was selected as mucoadhesive polymer both to pro...

in this study, the effectiveness of chitosan coating treatment to control weight loss and maintaining fruit quality of apricot was investigated. fruits were coated with 0.25%, 0.5% and 0.75% chitosan as well as distilled water (control). following treatments, fruits were stored at 0?c and 80 ? 2% relative humidity for 25 days. the weight loss, total soluble solids (tss), titratable acidity (ta)...

Chitosan has attracted much interest due to its special physical and chemical properties related to immunochemistry. The aim of this commentary is to appraise chitosan as an attractive functional polymer for medicine applications, which contributes to the development of chitosan for the immunochemistry. As reported, Chitosan has been used for immunochemistry purpose, such as functional food for...

Nanospheres are being developed for the oral delivery of peptide-based drugs such as insulin. Mucoadhesive, biodegradable, biocompatible, and acid-protective biomaterials are described using a combination of natural polyelectrolytes, with particles formulated through nanoemulsion dispersion followed by triggered in situ gel complexation. Biomaterials meeting these criteria include alginate, dex...

Antimicrobial packaging is one of the most promising active packaging systems. Antimicrobial packaging is the packaging system that is able to kill or inhibit spoilage and pathogenic microorganisms that are contaminating foods. A tremendous effort has been made over the last decade to develop and test films with antimicrobial properties to improve food safety and shelf life. For food preservati...

Polyphenol-rich grape seed extract (0.1 w/w%) was incorporated in liposomes (1 w/w% soy lecithin) by high pressure homogenization (22,500 psi) and coated with chitosan (0.1 w/w%). Primary liposomes and chitosan-coated secondary liposomes containing grape seed extract showed good physical stability during 98 days of storage. Most of the polyphenols were incorporated in the shell of the liposomes...

Textile chitosan fiber scaffolds were developed and tested in terms of biocompatibility for human bone marrow stromal cells (hBMSCs). A part of the scaffolds was further modified by coating with fibrillar collagen type I in order to biologize the surface. hBMSCs of two donors were used for cell culture experiments in vitro. Confocal laser scanning microscopy (CLSM) as well as scanning electron ...

A series of cellulose/soy protein membranes (CSM) was coated with chitosan to improve the mechanical properties, cytocompatibility, and hemocompatibility. The original CSM and chitosan-coated CSM (CH/CSM) were characterized by Fourier transform infrared spectroscopy, X-ray diffraction analysis, scanning electron microscopy, water contact angle testing, and tensile testing. CH/CSM had a smoother...